{"id":"W4311660588","doi":"10.1152/physiol.00020.2022","title":"RANKL and RANK in Cancer Therapy","year":2022,"lang":"en","type":"review","venue":"Physiology","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"T. Von Zastrow Foundation; Bundesministerium für Bildung, Wissenschaft und Forschung; Austrian Science Fund; Österreichischen Akademie der Wissenschaften; Canada Research Chairs","keywords":"RANKL; Immune system; Activator (genetics); RANK Ligand; Receptor; Biology; Cancer; Immunology; Cancer research; Bioinformatics; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005545002,0.0007265456,0.001131094,0.001739676,0.0002504514,0.001106541,0.0008966743,0.001176482,0.005531722],"category_scores_gemma":[0.0005798518,0.0002100781,0.0004313214,0.001379552,0.0004887855,0.001109041,0.0008306013,0.002886852,0.003406032],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007124562,"about_ca_system_score_gemma":0.0009141794,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007586936,"about_ca_topic_score_gemma":0.001769902,"domain_scores_codex":[0.9997979,0.00004098265,0.00002003096,0.00002462802,0.00009432137,0.00002226234],"domain_scores_gemma":[0.9997951,0.00008295503,0.00002292998,0.000007901787,0.00005907127,0.00003206086],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009957405,0.0000722928,0.00008265518,0.008556978,0.00007280534,0.0001959562,0.00004243127,0.0003870095,0.001686897,0.007261154,0.07584679,0.9056954],"study_design_scores_gemma":[0.00001483712,0.00004291105,0.0002080269,0.001450571,0.00003644325,0.0005928674,0.00001781456,0.00004990893,0.0002132877,0.001809676,0.9955553,0.000008353514],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00004766524,0.9983183,0.00007546272,0.0003771321,0.0003346223,0.000002967882,0.0000119552,0.000006564764,0.0008252931],"genre_scores_gemma":[0.0004801777,0.9976114,0.0001185685,0.0002928415,0.0003548904,0.00000592661,0.00002895036,0.000001932246,0.001105256],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005531722,"threshold_uncertainty_score":0.01850545,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05341453845394691,"score_gpt":0.3546788998724221,"score_spread":0.3012643614184752,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}