{"id":"W4311663966","doi":"10.1182/hematology.2022000334","title":"Antibodies and bispecifics for multiple myeloma: effective effector therapy","year":2022,"lang":"en","type":"review","venue":"Hematology","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Daratumumab; Antibody; Monoclonal antibody; Medicine; Antigen; Multiple myeloma; clone (Java method); Cancer research; Immunotherapy; Immunology; Bispecific antibody; Immune system; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002512436,0.0005061654,0.002827029,0.0003462384,0.0002311508,0.00001898533,0.0001270631,0.0003210889,0.0002278861],"category_scores_gemma":[0.0006225107,0.0003509733,0.000529528,0.0001980439,0.0001827497,0.00002819623,0.0001378853,0.000432751,0.00006156563],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001406117,"about_ca_system_score_gemma":0.0001772737,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000164159,"about_ca_topic_score_gemma":0.000008608692,"domain_scores_codex":[0.9977866,0.0003546292,0.0004030397,0.0006823178,0.0002163303,0.0005570385],"domain_scores_gemma":[0.9947576,0.004345039,0.0001924121,0.0004391005,0.00005644799,0.0002094141],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004091464,0.0002678797,0.00137197,0.02386831,0.001293125,0.0003930272,0.00004921692,6.842817e-9,0.000002569215,0.0002885625,0.001171144,0.970885],"study_design_scores_gemma":[0.004083429,0.001135105,0.0003822282,0.001444429,0.0004591801,0.00159677,0.00001825012,0.00001450528,0.00003445261,0.00003078685,0.990548,0.0002528485],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004970721,0.9907136,0.00003730862,0.00003650465,0.0002652557,0.007809554,0.0002867458,0.00008683268,0.000267151],"genre_scores_gemma":[0.0002134565,0.9926153,0.0006184297,0.00003253036,0.0001262379,0.005097946,0.000922932,0.0001058144,0.0002673438],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9893768,"threshold_uncertainty_score":0.9998942,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0949432377112657,"score_gpt":0.4019331827898597,"score_spread":0.306989945078594,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}