{"id":"W4311663966","doi":"10.1182/hematology.2022000334","title":"Antibodies and bispecifics for multiple myeloma: effective effector therapy","year":2022,"lang":"en","type":"review","venue":"Hematology","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Daratumumab; Antibody; Monoclonal antibody; Medicine; Antigen; Multiple myeloma; clone (Java method); Cancer research; Immunotherapy; Immunology; Bispecific antibody; Immune system; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001154221,0.000787248,0.0005801423,0.000779606,0.0002190923,0.00129264,0.000666832,0.001327472,0.004122159],"category_scores_gemma":[0.0006948486,0.0002888206,0.0003687304,0.0005337979,0.0006178872,0.001845356,0.001156098,0.003052854,0.003416044],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001163439,"about_ca_system_score_gemma":0.0003851411,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002327394,"about_ca_topic_score_gemma":0.0003745392,"domain_scores_codex":[0.9996075,0.00008984149,0.00002275645,0.00006043713,0.0001540173,0.00006552978],"domain_scores_gemma":[0.9998493,0.00003654902,0.00002615408,0.00001338259,0.00004301228,0.00003162683],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005245662,0.0004611399,0.0004390868,0.00221372,0.0001260172,0.0003995814,0.0001670382,0.001596055,0.08283936,0.1097202,0.06816415,0.7333491],"study_design_scores_gemma":[0.0001578258,0.000691088,0.0003664217,0.0002969157,0.00004679653,0.0009413558,0.0000239118,0.001180801,0.04103215,0.01664635,0.9385815,0.00003488382],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01656183,0.8843345,0.04585309,0.01362051,0.004876802,0.0002763907,0.0003900497,0.0007207797,0.0333661],"genre_scores_gemma":[0.1909158,0.6798652,0.03956439,0.01864108,0.005020925,0.0007307287,0.001144989,0.000305621,0.06381124],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004122159,"threshold_uncertainty_score":0.01379001,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0949432377112657,"score_gpt":0.4019331827898597,"score_spread":0.306989945078594,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}