{"id":"W4311676391","doi":"10.3390/cells11233939","title":"Phytocannabinoids Stimulate Rejuvenation and Prevent Cellular Senescence in Human Dermal Fibroblasts","year":2022,"lang":"en","type":"article","venue":"Cells","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Lethbridge","funders":"Natural Sciences and Engineering Research Council of Canada; Mitacs","keywords":"Cannabidiol; Wound healing; Viability assay; Pharmacology; Chemistry; Human skin; Senescence; Cell growth; Oxidative stress; Cell biology; Dermal fibroblast; Cell; Fibroblast; Biology; Biochemistry; In vitro; Medicine; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001136191,0.0001917453,0.0002679737,0.0002246386,0.0001269426,0.0001923342,0.0001109779,0.0001665791,0.001591365],"category_scores_gemma":[0.0000815743,0.00009704634,0.0003366293,0.000160487,0.0001092112,0.0001035828,0.0001428226,0.0003360489,0.0003649566],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001639092,"about_ca_system_score_gemma":0.0001869768,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001424318,"about_ca_topic_score_gemma":0.002829739,"domain_scores_codex":[0.999911,0.00001249033,0.00001448667,0.00001695589,0.00002357388,0.00002149565],"domain_scores_gemma":[0.9999266,0.0000159618,0.0000126401,0.00001457455,0.00001350749,0.00001679291],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002766778,0.00009558675,0.0002399421,0.00004986566,0.000005307947,0.00005047152,0.00002911097,0.00003540605,0.9971571,0.00002398377,0.00005435472,0.001982058],"study_design_scores_gemma":[0.00004063024,0.001267253,0.007457738,0.000007638915,0.00002011163,0.0001372231,0.00006951906,0.0003355742,0.9888742,0.00002565865,0.001760652,0.000003693037],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942759,0.002345883,0.0007741474,0.00005944116,0.00003120218,0.00004128134,0.0004204465,0.00005053537,0.002001153],"genre_scores_gemma":[0.9921511,0.001684402,0.001443133,0.00009696531,0.00001171798,0.00005005013,0.0004961829,0.00001192806,0.004054548],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001591365,"threshold_uncertainty_score":0.005323589,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01043045439958916,"score_gpt":0.2708821676817544,"score_spread":0.2604517132821652,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}