{"id":"W4311676391","doi":"10.3390/cells11233939","title":"Phytocannabinoids Stimulate Rejuvenation and Prevent Cellular Senescence in Human Dermal Fibroblasts","year":2022,"lang":"en","type":"article","venue":"Cells","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Lethbridge","funders":"Natural Sciences and Engineering Research Council of Canada; Mitacs","keywords":"Cannabidiol; Wound healing; Viability assay; Pharmacology; Chemistry; Human skin; Senescence; Cell growth; Oxidative stress; Cell biology; Dermal fibroblast; Cell; Fibroblast; Biology; Biochemistry; In vitro; Medicine; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003640844,0.000124915,0.0001947271,0.0001932234,0.0001824322,0.00002294993,0.00009464681,0.0000453745,0.0004750179],"category_scores_gemma":[0.00001308014,0.0001287034,0.00005540459,0.0003030013,0.00007123157,0.00005713708,0.0002032933,0.0003601631,0.000007140327],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001995169,"about_ca_system_score_gemma":0.0001276945,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001013059,"about_ca_topic_score_gemma":0.00001357314,"domain_scores_codex":[0.9985582,0.0001067685,0.0002358733,0.0003323831,0.0004370596,0.0003297284],"domain_scores_gemma":[0.9995055,0.000005962073,0.00005012569,0.0002397277,0.0000517781,0.0001469057],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001152423,0.0003291702,0.003822637,0.0002077975,0.00001145518,0.0002549405,0.0006320524,0.001060777,0.9711775,0.00009525465,0.01945907,0.002834091],"study_design_scores_gemma":[0.005094149,0.001851315,0.09258531,0.0001784416,0.00005092021,0.0001329759,0.0007020676,0.01042054,0.7520949,0.0004164252,0.1358916,0.0005813518],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953538,0.0004179342,0.00005970064,0.002677626,0.00009784732,0.0006226638,0.00001019325,0.00002732305,0.0007328911],"genre_scores_gemma":[0.980236,0.00001740326,0.00003919837,0.0002244331,0.00006387709,0.0001050875,0.00002890066,0.00002326357,0.01926183],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2190826,"threshold_uncertainty_score":0.5248373,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01043045439958916,"score_gpt":0.2708821676817544,"score_spread":0.2604517132821652,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}