{"id":"W4311679896","doi":"10.1182/hematology.2022000357","title":"Clinical screening for Ph-like ALL and the developing role of TKIs","year":2022,"lang":"en","type":"article","venue":"Hematology","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"National Cancer Institute","keywords":"Minimal residual disease; ABL; Immunotherapy; Medicine; Cancer research; Lymphoblastic Leukemia; Acute lymphocytic leukemia; Disease; Lineage (genetic); Immunology; Leukemia; Gene; Biology; Oncology; Internal medicine; Receptor; Genetics; Immune system; Tyrosine kinase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00100571,0.00006858751,0.0004179879,0.00005704555,0.0001116732,0.000002780805,0.0001246401,0.00006042839,0.00006838323],"category_scores_gemma":[0.0005887402,0.00004727073,0.0000788193,0.00009377767,0.0003120211,0.00001331277,0.000313593,0.000209537,0.00000257193],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005050706,"about_ca_system_score_gemma":0.0002990111,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003733487,"about_ca_topic_score_gemma":0.000005348481,"domain_scores_codex":[0.9988803,0.000166123,0.0003543774,0.0001897324,0.0001781221,0.0002313752],"domain_scores_gemma":[0.9976681,0.001920327,0.00009561228,0.0001935017,0.00006644442,0.00005595667],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","study_design_scores_codex":[0.02119085,0.0005184614,0.1946223,0.001352061,0.002321732,0.0003692997,0.006073388,0.00003588646,0.002053964,0.6277751,0.06181221,0.0818747],"study_design_scores_gemma":[0.09987676,0.002741835,0.01933911,0.0002702367,0.000888078,0.01595933,0.01255071,0.1153172,0.0054263,0.02693553,0.7000089,0.000686077],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.939783,0.003137456,0.03406252,0.01903069,0.0002968532,0.00170473,0.00002214644,0.00006296911,0.001899657],"genre_scores_gemma":[0.9789169,0.00005505299,0.01801439,0.002480902,0.00005827299,0.0001758842,0.00001350551,0.00001938421,0.0002657371],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6381966,"threshold_uncertainty_score":0.1927644,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05549048109893816,"score_gpt":0.3774807361570138,"score_spread":0.3219902550580757,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}