{"id":"W4311702531","doi":"10.1083/jcb.202108091","title":"The α-Catenin mechanosensing M region is required for cell adhesion during tissue morphogenesis","year":2022,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; Ted Rogers Centre for Heart Research; University of Toronto","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Morphogenesis; Catenin; Cell biology; Cell adhesion; Cell; Biology; Wnt signaling pathway; Genetics; Signal transduction; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007502924,0.0001590162,0.0001373159,0.0001431115,0.0002085293,0.0003264843,0.0001230138,0.000154236,0.0006464072],"category_scores_gemma":[0.0001529375,0.0001339257,0.00009700156,0.0001164833,0.0001722296,0.0001933267,0.0002080754,0.0002462751,0.0002009352],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002474033,"about_ca_system_score_gemma":0.0001802212,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005957056,"about_ca_topic_score_gemma":0.001011785,"domain_scores_codex":[0.9999087,0.000008683292,0.000007141237,0.00002426638,0.0000278157,0.00002348268],"domain_scores_gemma":[0.9998834,0.00001220185,0.00003483968,0.0000138151,0.00001307914,0.00004262174],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001483214,0.000002080045,0.0003731404,0.000004688115,6.336367e-7,0.00002710851,0.000003962171,0.00001397018,0.9992254,0.0000488833,0.000003531224,0.000281858],"study_design_scores_gemma":[0.000007066001,0.0000747472,0.09339212,0.000006716241,0.000009935147,0.0008371226,0.00006399768,0.001622301,0.9020957,0.0001540763,0.001731108,0.000005124228],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977891,0.0003703205,0.001168358,0.00002352796,0.000003946147,0.000003238091,0.00005259342,0.00001878061,0.0005701288],"genre_scores_gemma":[0.9988639,0.00008311363,0.0005126299,0.000007923255,0.000001375233,0.000003261256,0.00006286515,0.000003666278,0.00046116],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006464072,"threshold_uncertainty_score":0.002162457,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0150521834419314,"score_gpt":0.2475418055917306,"score_spread":0.2324896221497992,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}