{"id":"W4311764040","doi":"10.1016/j.talanta.2022.124156","title":"A precise and rapid early pregnancy test: Development of a novel and fully automated electrochemical point-of-care biosensor for human urine samples","year":2022,"lang":"en","type":"article","venue":"Talanta","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Detection limit; Chemistry; Biosensor; Reproducibility; Chromatography; Urine; Luteinizing hormone; Point of care; Human chorionic gonadotropin; Point-of-care testing; Hormone; Biochemistry; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001061831,0.0009527993,0.001042134,0.0005319379,0.0002965454,0.0006573851,0.001788938,0.002511782,0.0007826571],"category_scores_gemma":[0.001309221,0.0006653725,0.0005246891,0.0002933359,0.0003611548,0.0007252428,0.0009795743,0.001220722,0.000853922],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003593752,"about_ca_system_score_gemma":0.001007911,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006578226,"about_ca_topic_score_gemma":0.001285393,"domain_scores_codex":[0.9985771,0.0002294471,0.00006382901,0.0003126646,0.0007294873,0.00008754603],"domain_scores_gemma":[0.9995081,0.0001284423,0.00005040477,0.00004371877,0.0001995986,0.00006970799],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001687086,0.0001127836,0.0009555251,0.0001774088,0.0000360741,0.0001195155,0.00004855964,0.0002070901,0.9552633,0.0003331453,0.001096343,0.04148145],"study_design_scores_gemma":[0.00006180655,0.000930131,0.004390669,0.00002928458,0.00006912466,0.002777633,0.00003987616,0.01519325,0.965722,0.000302799,0.01040103,0.00008252948],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.1416211,0.008461065,0.8390219,0.001710752,0.000917263,0.001011514,0.0008547654,0.004186039,0.002215618],"genre_scores_gemma":[0.388698,0.002832152,0.5989307,0.001710854,0.0002501936,0.0007288379,0.0007234006,0.0001376232,0.005988231],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.002511782,"threshold_uncertainty_score":0.005615532,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01333839604116764,"score_gpt":0.2718678595841189,"score_spread":0.2585294635429512,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}