{"id":"W4311785325","doi":"10.3390/curroncol29120756","title":"CDK4/6 Inhibitors as Upfront Treatment in a Patient with Breast Cancer Presenting with a Clinical Critic Situation: A Case Report and Review of the Literature","year":2022,"lang":"en","type":"review","venue":"Current Oncology","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Metastatic breast cancer; Letrozole; Breast cancer; Chemotherapy; Clinical trial; Cancer; Oncology; Population; Intensive care medicine; Internal medicine; Tamoxifen","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003795931,0.0004451046,0.002407432,0.0001294581,0.00008018386,0.000009059127,0.00009368934,0.0001519134,0.0001498504],"category_scores_gemma":[0.0001655586,0.0002235627,0.0002912423,0.0006215834,0.0002792303,0.00006132745,0.0001358658,0.0008536661,5.496506e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001348971,"about_ca_system_score_gemma":0.002955636,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001136827,"about_ca_topic_score_gemma":0.0002945928,"domain_scores_codex":[0.9967111,0.0006842163,0.001286005,0.0006760126,0.0003598356,0.0002828591],"domain_scores_gemma":[0.9974653,0.000331587,0.001247578,0.0005951496,0.0002262764,0.0001340967],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001926925,0.0007302531,0.001505402,0.05164908,0.0002915715,0.03041419,0.000765794,5.23729e-7,1.695713e-8,0.000004844189,0.0000793765,0.9143662],"study_design_scores_gemma":[0.001008095,0.0008635339,0.0001062969,0.1244205,0.00164008,0.2554046,0.0001155601,8.695177e-7,9.61165e-8,0.000003541252,0.6162938,0.0001430284],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002521637,0.9921981,0.000001852716,0.0007358171,0.0005846496,0.003721522,0.0001288773,0.00001642644,0.00009118849],"genre_scores_gemma":[0.0002715833,0.9964196,0.0000985158,0.0001423161,0.0003071473,0.002526889,0.0001191174,0.00004915025,0.00006568003],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9142233,"threshold_uncertainty_score":0.9116622,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1118065257088097,"score_gpt":0.4815901247787339,"score_spread":0.3697835990699242,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}