{"id":"W4311934208","doi":"10.1158/2326-6066.cir-22-0174","title":"Efficacy and Synergy with Cisplatin of an Adenovirus Vectored Therapeutic E1E2E6E7 Vaccine against HPV Genome–Positive C3 Cancers in Mice","year":2022,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Universiteit Leiden; National Institutes of Health; Eurostars; Bundesministerium für Bildung und Forschung; Institut de recherche en santé mentale; European Commission","keywords":"Medicine; Virology; Cisplatin; Immunotherapy; Genome; Cancer research; Immunology; Biology; Immune system; Internal medicine; Chemotherapy; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002470034,0.0005252065,0.0005490891,0.0004069638,0.0001165701,0.0003110429,0.0002807771,0.00052001,0.0006466623],"category_scores_gemma":[0.0001639955,0.0001704796,0.0003315712,0.0001677426,0.0003056647,0.0002719917,0.0001559184,0.0007813516,0.0002426558],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002246508,"about_ca_system_score_gemma":0.0004174536,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006693534,"about_ca_topic_score_gemma":0.0008107233,"domain_scores_codex":[0.9997836,0.00004822089,0.00001856082,0.00003938749,0.00004431793,0.00006584549],"domain_scores_gemma":[0.9998146,0.00003589593,0.00004235475,0.00002658388,0.00001920347,0.000061495],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002694833,0.001085238,0.0003785798,0.0001205656,0.00003608792,0.0000474741,0.00004280331,0.001027258,0.9856397,0.0002498111,0.0001533391,0.008524421],"study_design_scores_gemma":[0.0004160487,0.01720286,0.00287529,0.00002134406,0.00009049438,0.0001651856,0.00002037038,0.003072598,0.9739653,0.0001068395,0.002047547,0.00001624291],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969985,0.0009143934,0.0006490764,0.00008909225,0.00005878236,0.00006212687,0.0001815012,0.00006957568,0.0009769051],"genre_scores_gemma":[0.9967942,0.0006899486,0.0008629096,0.00004464601,0.00002338881,0.00005477013,0.0002354642,0.00001631358,0.001278475],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006693534,"threshold_uncertainty_score":0.002163291,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0266743178636918,"score_gpt":0.3423913271875536,"score_spread":0.3157170093238618,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}