{"id":"W4311934208","doi":"10.1158/2326-6066.cir-22-0174","title":"Efficacy and Synergy with Cisplatin of an Adenovirus Vectored Therapeutic E1E2E6E7 Vaccine against HPV Genome–Positive C3 Cancers in Mice","year":2022,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Universiteit Leiden; National Institutes of Health; Eurostars; Bundesministerium für Bildung und Forschung; Institut de recherche en santé mentale; European Commission","keywords":"Medicine; Virology; Cisplatin; Immunotherapy; Genome; Cancer research; Immunology; Biology; Immune system; Internal medicine; Chemotherapy; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009956963,0.0002195135,0.0003362728,0.0003958695,0.0003105793,0.0000201052,0.0006549511,0.000150131,0.0002138322],"category_scores_gemma":[0.00004104437,0.0002102401,0.00003862148,0.0007814784,0.0005184997,0.00001085352,0.0004644576,0.0008057149,0.000002057579],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000399633,"about_ca_system_score_gemma":0.001087312,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001361163,"about_ca_topic_score_gemma":0.003429157,"domain_scores_codex":[0.9966295,0.001183487,0.0002890131,0.000697536,0.0004328379,0.0007676135],"domain_scores_gemma":[0.9988556,0.0001108612,0.00009493857,0.000569251,0.0002656695,0.0001036609],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.02571449,0.0001725051,0.001110807,0.00002053048,0.0003853507,0.00003921883,0.0005854208,0.002555425,0.9403105,0.0000175368,0.00002193664,0.02906632],"study_design_scores_gemma":[0.01299443,0.03040577,0.07636286,0.00005044433,0.00003482971,0.00006837168,0.002718189,0.0004841741,0.8718227,0.00005777477,0.004304215,0.0006962661],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9704391,0.02814996,0.000006624971,0.00029928,0.0000548602,0.0006411857,0.0001032797,0.000009388087,0.0002963046],"genre_scores_gemma":[0.9954453,0.003224556,0.00002525931,0.0001665195,0.00007145463,0.0005501608,0.0001622354,0.00006024391,0.0002943324],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07525206,"threshold_uncertainty_score":0.8573343,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0266743178636918,"score_gpt":0.3423913271875536,"score_spread":0.3157170093238618,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}