{"id":"W4311946762","doi":"10.3389/fbioe.2022.1103007","title":"Editorial: Current approaches to CRISPR/Cas9 delivery","year":2022,"lang":"en","type":"editorial","venue":"Frontiers in Bioengineering and Biotechnology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"CRISPR; Genome editing; Gene delivery; Computational biology; Cas9; Current (fluid); Genetic enhancement; Biology; Gene; Genetics; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.000293734,0.0004885609,0.000511798,0.0006464915,0.00007537287,0.00003693927,0.0005419633,0.001614957,0.000004220304],"category_scores_gemma":[0.0002715999,0.0005512846,0.0001041134,0.0003495629,0.00008554698,0.000003557786,0.0007090811,0.001252232,0.000002012322],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009350203,"about_ca_system_score_gemma":0.0001012544,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002527013,"about_ca_topic_score_gemma":0.00001257218,"domain_scores_codex":[0.9977624,0.0000315789,0.0003608974,0.0009465631,0.0003085791,0.0005900196],"domain_scores_gemma":[0.9991651,0.00002334642,0.00006713719,0.0005822174,0.00003292357,0.0001292573],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005427925,0.00003602642,0.00005165693,0.000151691,0.00006273594,0.000004609046,0.00002570156,0.001991019,0.003918223,0.00001250979,0.9814724,0.01221915],"study_design_scores_gemma":[0.0003842572,0.0003091572,0.000009051533,0.00004959589,0.00003026495,0.000004164007,0.00008971223,0.0004132941,0.00613678,0.00001842871,0.9919517,0.0006035843],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"editorial","genre_scores_codex":[0.001307876,0.02065475,0.03220467,0.000173462,0.9450256,0.0003277844,0.0001734248,0.0001139123,0.00001848709],"genre_scores_gemma":[0.002384029,0.01155991,0.008255637,0.00001457141,0.9765323,0.0002330095,0.000691967,0.0001387513,0.0001898699],"genre_candidate":"editorial","genre_consensus":"editorial","teacher_disagreement_score":0.03150663,"threshold_uncertainty_score":0.9996939,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01122349659478123,"score_gpt":0.2471172882940206,"score_spread":0.2358937916992394,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}