{"id":"W4311976721","doi":"10.1007/s00415-022-11512-1","title":"Language impairment in the genetic forms of behavioural variant frontotemporal dementia","year":2022,"lang":"en","type":"article","venue":"Journal of Neurology","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Western University; Montreal Neurological Institute and Hospital; University of Toronto; Occupational Cancer Research Centre; Health Sciences Centre; McGill University Health Centre; Sunnybrook Health Science Centre; Université Laval","funders":"NIHR Cambridge Biomedical Research Centre; Instituto de Salud Carlos III; Medical Research Council; Tau Consortium; UK Dementia Research Institute; Stichting Dioraphte; Networks of Centres of Excellence of Canada; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico; Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta; Università degli Studi di Brescia; Stockholms Läns Landsting; Universidade de Coimbra; University of Toronto; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Alzheimer's Society; Alzheimer Society; Ministero della Salute; Toronto Rehabilitation Institute; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas; Wolfson Foundation; Wellcome Trust; University College London; University of Cambridge; Bundesministerium für Bildung und Forschung; National Institute for Health and Care Research; Karolinska Institutet; Weston Brain Institute; ZonMw; Brain Research UK; Alzheimer's Research Trust; National Brain Appeal; Agence Nationale de la Recherche; Deutsche Forschungsgemeinschaft; University Health Network; Università degli Studi di Milano; EU Joint Programme – Neurodegenerative Disease Research; Alzheimer Nederland; Sunnybrook Research Institute; Fundació la Marató de TV3; Canadian Institutes of Health Research; London School of Hygiene and Tropical Medicine","keywords":"Frontotemporal dementia; Psychology; Primary progressive aphasia; Audiology; Boston Naming Test; C9orf72; Verbal fluency test; Aphasia; Fluency; Dementia; Neuropsychology; Cognitive psychology; Medicine; Pathology; Neuroscience; Cognition; Disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006502073,0.00006474656,0.0002336428,0.0001433109,0.00003920239,0.0000044769,0.00024923,0.00003079062,0.000525813],"category_scores_gemma":[0.00002629601,0.00003798825,0.000105857,0.0001280718,0.00004721488,0.000034301,0.0001132076,0.0006000477,0.00000110662],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004077053,"about_ca_system_score_gemma":0.00009234707,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000163509,"about_ca_topic_score_gemma":0.00002860997,"domain_scores_codex":[0.9984681,0.0003146612,0.0004414755,0.00008036584,0.0004883281,0.000207075],"domain_scores_gemma":[0.9994757,0.00004751165,0.0002275397,0.0001552801,0.00003981578,0.00005419073],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002165534,0.0009663,0.9576999,0.00002282038,0.0001116986,0.009111074,0.004058325,0.0002456311,0.02214274,0.00004518184,0.001535885,0.00189494],"study_design_scores_gemma":[0.001836318,0.005893848,0.9872465,0.000004184753,0.00005610492,0.004034619,0.0002079439,0.000214799,0.00003371762,0.00009026375,0.0003521954,0.00002953349],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925503,0.0003799953,0.00001553853,0.006680225,0.0001184654,0.0001872602,0.000003564875,0.000001843955,0.00006285414],"genre_scores_gemma":[0.9985673,0.00002524253,0.0001199906,0.0011893,0.00006153597,0.000008024587,0.000001696953,0.000008450065,0.00001843888],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02954661,"threshold_uncertainty_score":0.5757284,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03332022241091582,"score_gpt":0.2954502460422622,"score_spread":0.2621300236313464,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}