{"id":"W4312032193","doi":"10.1007/s11357-022-00702-4","title":"Frailty and functional brain connectivity (FBC) in older adults with mild cognitive impairment (MCI): baseline results from the SYNERGIC Trial","year":2022,"lang":"en","type":"article","venue":"GeroScience","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute; University of British Columbia; Vancouver Coastal Health; Wilfrid Laurier University; Dalhousie University; University of Waterloo; Lawson Health Research Institute; Western University; Parkwood Institute; University of Calgary","funders":"Consortium canadien en neurodégénérescence associée au vieillissement; Canadian Institutes of Health Research; Government of Ontario","keywords":"Dementia; Cognitive impairment; Hippocampus; Medicine; Functional connectivity; Sample size determination; Frailty Index; Biomarker; Default mode network; Cognition; Internal medicine; Psychology; Neuroscience; Oncology; Psychiatry; Biology; Disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001275453,0.001358653,0.002546369,0.000251206,0.0005700179,0.00115673,0.0005229433,0.001369304,0.002423581],"category_scores_gemma":[0.002578869,0.0003971116,0.001833716,0.0005480852,0.0004617568,0.0008881057,0.0006920683,0.001706253,0.0003946473],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005683649,"about_ca_system_score_gemma":0.0006520262,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003535092,"about_ca_topic_score_gemma":0.007009947,"domain_scores_codex":[0.9996161,0.0001355526,0.00004138694,0.00009121993,0.00004175958,0.0000739913],"domain_scores_gemma":[0.9991152,0.0001839221,0.0002476234,0.00009800109,0.00008877139,0.0002665247],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7598739,0.00675045,0.1568026,0.001506151,0.01959237,0.0002251062,0.0003311938,0.001406405,0.001858358,0.0003409957,0.004502015,0.04681053],"study_design_scores_gemma":[0.1687789,0.06597538,0.7372206,0.0004872114,0.02069274,0.0002956403,0.0003804455,0.0011038,0.0005910652,0.001517771,0.002819609,0.0001369765],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922409,0.005127523,0.00007561264,0.0002705645,0.00007106437,0.0001055749,0.0009536149,0.00001227688,0.001142908],"genre_scores_gemma":[0.9943481,0.001930877,0.0001932005,0.0002950646,0.0002276901,0.0002351915,0.002061251,0.000005201992,0.0007033863],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003535092,"threshold_uncertainty_score":0.008107722,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02968326114452375,"score_gpt":0.2954643518448081,"score_spread":0.2657810907002844,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}