{"id":"W4312055525","doi":"10.1016/j.ijrobp.2022.12.015","title":"Long-Term Update of NRG/RTOG 0522: A Randomized Phase 3 Trial of Concurrent Radiation and Cisplatin With or Without Cetuximab in Locoregionally Advanced Head and Neck Cancer","year":2022,"lang":"en","type":"article","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Head and Neck Cancer Studies","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre; Centre Hospitalier de l’Université de Montréal","funders":"National Cancer Institute; NRG Oncology; Eli Lilly and Company","keywords":"Cetuximab; Medicine; Head and neck cancer; Hazard ratio; Common Terminology Criteria for Adverse Events; Oncology; Internal medicine; Radiation therapy; Confidence interval; Randomized controlled trial; Cisplatin; Cancer; Chemotherapy; Colorectal cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005110065,0.001582727,0.003642844,0.0004732765,0.0007697817,0.002113996,0.001757166,0.002232848,0.007413066],"category_scores_gemma":[0.002995095,0.0008671527,0.002898952,0.000652838,0.00140597,0.002121125,0.0006828802,0.006022503,0.001789595],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001684396,"about_ca_system_score_gemma":0.002774607,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002709633,"about_ca_topic_score_gemma":0.01117888,"domain_scores_codex":[0.9986259,0.0007349267,0.00007562129,0.0002281734,0.0001326381,0.0002028317],"domain_scores_gemma":[0.9978369,0.0004841522,0.0004073362,0.0002148258,0.000155739,0.0009011579],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8844731,0.01362888,0.003208383,0.0009075877,0.003817811,0.00009858073,0.0003383298,0.001496174,0.007180548,0.0003398909,0.01077782,0.07373302],"study_design_scores_gemma":[0.9055567,0.08001664,0.006105384,0.00005829353,0.00149485,0.00008483914,0.00007964871,0.0005749827,0.0007391758,0.000258482,0.004990988,0.00004001754],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9677443,0.01151351,0.001351827,0.004380255,0.001206556,0.003385463,0.005338578,0.0004142197,0.004665208],"genre_scores_gemma":[0.962478,0.0052747,0.004461647,0.007059406,0.000818419,0.004327356,0.008249623,0.00018886,0.007142041],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007413066,"threshold_uncertainty_score":0.02702498,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02799382484463132,"score_gpt":0.3870150063841177,"score_spread":0.3590211815394864,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}