{"id":"W4312075225","doi":"10.1038/s41467-022-35383-2","title":"Astrocytes amplify neurovascular coupling to sustained activation of neocortex in awake mice","year":2022,"lang":"en","type":"article","venue":"Nature Communications","topic":"Traumatic Brain Injury and Neurovascular Disturbances","field":"Medicine","cited_by":96,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Government of Canada; University of Calgary","keywords":"Neocortex; Neurovascular bundle; Neuroscience; Coupling (piping); Biology; Cell biology; Anatomy; Materials science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003662362,0.0007415949,0.0004100818,0.0009088134,0.0003769513,0.0005253372,0.0004635151,0.0006516864,0.003106494],"category_scores_gemma":[0.0001978777,0.0004647544,0.0005629892,0.0002090626,0.000814834,0.0003598778,0.0004633611,0.001756005,0.0007058134],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000562792,"about_ca_system_score_gemma":0.0003461498,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007438546,"about_ca_topic_score_gemma":0.001829489,"domain_scores_codex":[0.9996554,0.00003390934,0.00003554014,0.00008633261,0.00009913528,0.00008976804],"domain_scores_gemma":[0.9995147,0.00004525882,0.000157407,0.00005443156,0.00003849049,0.0001897053],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002967719,0.00008017223,0.0000902445,0.00002559855,0.000007114937,0.0001152631,0.00003281535,0.00005109113,0.9981624,0.0002589634,0.00007108565,0.0008084386],"study_design_scores_gemma":[0.0001415714,0.001151218,0.004028589,0.00001996129,0.00003744525,0.0003778285,0.0001146922,0.001042743,0.9889711,0.000350096,0.003750899,0.000013727],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9865054,0.0009287204,0.006976832,0.0004612134,0.0001512524,0.0001511313,0.001342857,0.0004708293,0.003011796],"genre_scores_gemma":[0.9770802,0.001079793,0.007024514,0.0003040869,0.00005154697,0.0003411514,0.0009197872,0.00021481,0.01298409],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003106494,"threshold_uncertainty_score":0.01039231,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02325950706191768,"score_gpt":0.3026037358317125,"score_spread":0.2793442287697948,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}