{"id":"W4312082133","doi":"10.1053/j.gastro.2022.12.010","title":"Intestinal Permeability Improvement With Nutritional Therapy Is Associated With Specific Microbiome Profiles and Functional Pathways in Pediatric Crohn's Disease","year":2022,"lang":"en","type":"letter","venue":"Gastroenterology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research; Women and Children's Health Research Institute; U.S. Department of Veterans Affairs","keywords":"Intestinal permeability; Gastroenterology; Lactulose; Internal medicine; Dietary therapy; Microbiome; Crohn's disease; Medical nutrition therapy; Medicine; Disease; Pediatric gastroenterology; Biology; Bioinformatics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008973262,0.0003292173,0.0009151442,0.0003363647,0.0008352483,0.0008717888,0.0004064939,0.004921714,0.00125289],"category_scores_gemma":[0.007520857,0.0002218858,0.0005037975,0.0004088702,0.000804994,0.0007290478,0.0003538536,0.005700499,0.0005427253],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001205637,"about_ca_system_score_gemma":0.0009575699,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002194629,"about_ca_topic_score_gemma":0.003875507,"domain_scores_codex":[0.9992958,0.0002517393,0.00009545563,0.00008491781,0.0001592742,0.0001128456],"domain_scores_gemma":[0.9969119,0.001866685,0.000245252,0.00009446441,0.0004438852,0.0004377393],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.002983833,0.0004694277,0.1696303,0.0004800491,0.000290754,0.06852061,0.0006476273,0.0005059119,0.004753375,0.003801007,0.6234326,0.1244845],"study_design_scores_gemma":[0.002004126,0.002538259,0.3632991,0.001419916,0.0009656643,0.1451612,0.00215388,0.006285139,0.004720116,0.01827427,0.452924,0.0002542461],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.08805319,0.01113623,0.000588507,0.8739498,0.01694171,0.00002405359,0.0002814292,0.0001058993,0.008919223],"genre_scores_gemma":[0.429185,0.00764287,0.001549797,0.4836775,0.07094817,0.00009336846,0.0002156674,0.00006931094,0.006618246],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.004921714,"threshold_uncertainty_score":0.008747578,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01267238663680722,"score_gpt":0.2038038181334942,"score_spread":0.1911314314966869,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}