{"id":"W4312083287","doi":"10.1016/j.pan.2022.12.011","title":"Design and execution of sham-controlled endoscopic trials in acute pancreatitis: Lessons learned from the SHARP trial","year":2022,"lang":"en","type":"review","venue":"Pancreatology","topic":"Pancreatitis Pathology and Treatment","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health","keywords":"Medicine; Pancreas divisum; Pancreatitis; Clinical trial; Randomized controlled trial; Acute pancreatitis; Placebo; Intensive care medicine; General surgery; Internal medicine; Alternative medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.2067223,0.001822762,0.0122371,0.0009541956,0.0006310088,0.005577116,0.003860986,0.005440026,0.002842846],"category_scores_gemma":[0.2411207,0.001065081,0.005953041,0.001416936,0.004790061,0.005485754,0.002334872,0.01030445,0.0005913771],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002518136,"about_ca_system_score_gemma":0.0082228,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001123241,"about_ca_topic_score_gemma":0.001787266,"domain_scores_codex":[0.8021478,0.1692165,0.01470033,0.00536151,0.00754566,0.001028322],"domain_scores_gemma":[0.6924699,0.2676337,0.0137216,0.01729,0.007207199,0.001677634],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.06860509,0.001287684,0.002608473,0.115595,0.02578978,0.0003076118,0.001257766,0.005888526,0.001848967,0.04314664,0.01280799,0.7208564],"study_design_scores_gemma":[0.2444688,0.03480081,0.01453756,0.164584,0.04579857,0.001214242,0.001407936,0.01247948,0.004327616,0.231586,0.2440678,0.0007271079],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01248153,0.8698394,0.07147747,0.01748577,0.009667025,0.01274081,0.0007057766,0.0002754141,0.005326725],"genre_scores_gemma":[0.2545932,0.3616473,0.3105542,0.02088727,0.007809997,0.0409459,0.0008242737,0.0004054782,0.002332499],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7932777,"threshold_uncertainty_score":0.9782527,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2198203438400307,"score_gpt":0.4155244729211465,"score_spread":0.1957041290811158,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}