{"id":"W4312086286","doi":"10.1002/alz.069370","title":"Conserved cell‐type specific signature of resilience to Alzheimer’s disease nominates role for excitatory cortical neurons","year":2022,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Neuroscience; Cognitive decline; Dementia; Biology; Neuropathology; Disease; Hippocampus; Alzheimer's disease; Psychology; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001737876,0.000232366,0.0001987743,0.0004177739,0.0001779132,0.0002484965,0.0001467286,0.000149277,0.001057711],"category_scores_gemma":[0.0001998143,0.000100631,0.0003068296,0.0002006203,0.0002528167,0.0001193855,0.0002870431,0.0003041905,0.0002134151],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001926401,"about_ca_system_score_gemma":0.0001827511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007049909,"about_ca_topic_score_gemma":0.001271513,"domain_scores_codex":[0.999895,0.000008069223,0.000008307808,0.00004512892,0.00002222922,0.00002132121],"domain_scores_gemma":[0.999838,0.0000182874,0.00005474042,0.0000262672,0.00003378569,0.00002897886],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002077358,0.00001932675,0.006855478,0.00003417218,0.00002300418,0.00006830183,0.00003502858,0.00005563872,0.9909865,0.00006312924,0.00004829737,0.001603413],"study_design_scores_gemma":[0.00002962249,0.0006788558,0.4776926,0.00002022513,0.0001460023,0.001535218,0.0002545372,0.001208973,0.5155126,0.0003873297,0.002508311,0.00002563969],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967438,0.0003755305,0.001688159,0.00004474162,0.00001091664,0.00001145834,0.0006744183,0.00002748738,0.0004235106],"genre_scores_gemma":[0.9970831,0.0002256414,0.001138296,0.00004950877,0.000004542559,0.00002196622,0.0007565752,0.000008857263,0.000711556],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001057711,"threshold_uncertainty_score":0.00353843,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03460415543881816,"score_gpt":0.3022275746610832,"score_spread":0.2676234192222651,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}