{"id":"W4312086649","doi":"10.1002/alz.067341","title":"Single and chronic administration of cellulose ethers rescue memory deficit in a transgenic mouse model of Alzheimer’s disease","year":2022,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Genetically modified mouse; Presenilin; Transgene; Amyloid (mycology); Disease; Dementia; Medicine; Pharmacology; Internal medicine; Alzheimer's disease; Chemistry; Pathology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002347577,0.0009148302,0.0006588083,0.0008765917,0.0002364661,0.0003305411,0.0004817818,0.0007459291,0.001373243],"category_scores_gemma":[0.0001223586,0.0002543544,0.0005564518,0.0002620394,0.0003813759,0.0004033902,0.000209285,0.001475436,0.0005133685],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003234325,"about_ca_system_score_gemma":0.0003447325,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00122588,"about_ca_topic_score_gemma":0.00154782,"domain_scores_codex":[0.9998019,0.00001976217,0.00002596566,0.00004649235,0.00004125854,0.00006464748],"domain_scores_gemma":[0.999751,0.00001346772,0.00007746997,0.00003044889,0.00002953905,0.00009805916],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007006866,0.0004713101,0.000191651,0.0000489044,0.00001670466,0.00007291719,0.00001895818,0.00004155318,0.9964747,0.00004837804,0.0001022537,0.001811831],"study_design_scores_gemma":[0.0001701094,0.006167863,0.005992916,0.00002828274,0.00009940714,0.0003133082,0.00006647695,0.0006820796,0.9838461,0.0001179062,0.002497208,0.00001832761],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994738,0.001441068,0.0015276,0.0001745866,0.0001066793,0.00005625239,0.0007410394,0.000192693,0.001022104],"genre_scores_gemma":[0.9842436,0.002100787,0.003353216,0.0001786434,0.00005327271,0.00019612,0.00128846,0.00005295375,0.008532939],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001373243,"threshold_uncertainty_score":0.004593909,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04909848059851053,"score_gpt":0.3003914750548346,"score_spread":0.2512929944563241,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}