{"id":"W4312086983","doi":"10.1002/alz.068100","title":"Two year cognitive and biomarker change in a racially diverse, middle‐aged, cohort at risk for Alzheimer’s disease","year":2022,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Biomarker; Cohort; Memory span; Medicine; Cognition; Cognitive decline; Demography; Incidence (geometry); Montreal Cognitive Assessment; Cohort study; Internal medicine; Psychology; Gerontology; Disease; Oncology; Cognitive impairment; Biology; Dementia; Psychiatry; Genetics; Working memory","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007777825,0.0003937343,0.0003347506,0.0008342878,0.001010431,0.0007173065,0.0003350168,0.0006088127,0.0009121787],"category_scores_gemma":[0.001372215,0.0002593164,0.0004832199,0.0006396631,0.0001908317,0.0007081827,0.0005775559,0.0006218682,0.0003807668],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003965001,"about_ca_system_score_gemma":0.0004795379,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.03554179,"about_ca_topic_score_gemma":0.02546375,"domain_scores_codex":[0.9997382,0.00004446544,0.00001809217,0.00008004748,0.00005026447,0.00006894564],"domain_scores_gemma":[0.9993638,0.00003608289,0.0001393037,0.00005830031,0.0001516403,0.0002509153],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004519635,0.0002283451,0.9973994,0.000003491982,0.00003734943,0.0001271264,0.0002280856,0.00001741576,0.0005535349,0.000006541618,0.0001171731,0.0008295961],"study_design_scores_gemma":[0.00000993816,0.0002253922,0.9992385,0.000001501686,0.00001734182,0.00008013516,0.0002155393,0.00005783732,0.00005257387,0.00000754891,0.00009129658,0.00000252537],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994802,0.00003547225,0.00002869783,0.00001546646,0.000003446248,0.000007934346,0.0003037695,0.000002471235,0.0001226351],"genre_scores_gemma":[0.9986849,0.00004264351,0.00007252765,0.00003601143,0.00000733284,0.00002024795,0.0007231372,0.000001529993,0.0004115318],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03554179,"threshold_uncertainty_score":0.07066983,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06678384001323856,"score_gpt":0.3388661915013816,"score_spread":0.272082351488143,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}