{"id":"W4312087075","doi":"10.1002/alz.063188","title":"Predictors of Alzheimer’s disease risk in women with bilateral oophorectomy from the UK Biobank","year":2022,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Baycrest Hospital; Women and Children’s Health Research Institute; University of Alberta; University of Toronto","funders":"Medical Research Council","keywords":"Biobank; Medicine; Disease; Logistic regression; Cognitive decline; Alzheimer's disease; Demography; Gynecology; Psychology; Internal medicine; Dementia; Bioinformatics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001080948,0.0002995692,0.0005149772,0.0013789,0.0004895553,0.000824274,0.0005512355,0.0004790401,0.004466094],"category_scores_gemma":[0.008926608,0.0003396814,0.0003564502,0.003432635,0.000271005,0.0005681223,0.001052545,0.0005246539,0.0009755497],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006637761,"about_ca_system_score_gemma":0.000492682,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.05763106,"about_ca_topic_score_gemma":0.05804892,"domain_scores_codex":[0.9987469,0.0003199929,0.0002819197,0.0002822762,0.0002133854,0.000155573],"domain_scores_gemma":[0.9954293,0.0007005826,0.002422087,0.0003828493,0.0007571005,0.0003080966],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002231944,0.00001790269,0.9915952,0.0001242244,0.00007098772,0.0001318331,0.0004048911,0.00003604615,0.0001765041,0.00006373331,0.004307755,0.002847715],"study_design_scores_gemma":[0.00002496539,0.00003813548,0.9951761,0.000128231,0.00005767562,0.0003398343,0.0004252884,0.0001220149,0.00006472892,0.0000661817,0.003546814,0.00001006849],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9630597,0.003297986,0.0004116555,0.0007355484,0.00006868774,0.0000845051,0.03000896,0.00001269363,0.002320316],"genre_scores_gemma":[0.9848567,0.001286262,0.0005125892,0.0003261202,0.00004853307,0.0001977453,0.01163859,0.00001093399,0.001122506],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05763106,"threshold_uncertainty_score":0.1145912,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006408199688340319,"score_gpt":0.2133445635943813,"score_spread":0.206936363906041,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}