{"id":"W4312087517","doi":"10.1002/alz.065988","title":"LDLR, VLDLR and APOBR in the pathophysiology of sporadic Alzheimer’s disease","year":2022,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Apolipoprotein E; Internal medicine; Pathophysiology; Apolipoprotein B; Receptor; Disease; Pathological; Endocrinology; LDL receptor; Psychology; Cholesterol; Biology; Medicine; Lipoprotein","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006499512,0.0002800894,0.0003165464,0.0007002578,0.0001658908,0.0005868745,0.0002856568,0.0002810712,0.001353492],"category_scores_gemma":[0.000703274,0.0001385967,0.0004558575,0.000612308,0.0001937844,0.0001240472,0.0002286642,0.0002936795,0.0002244354],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001668444,"about_ca_system_score_gemma":0.0002455897,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003506628,"about_ca_topic_score_gemma":0.003345801,"domain_scores_codex":[0.9998093,0.00006163953,0.00001323001,0.00006114893,0.00003044666,0.00002426012],"domain_scores_gemma":[0.9995414,0.0001139288,0.0001812741,0.00005202422,0.00004679295,0.00006462163],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002217795,0.00006908193,0.9688867,0.0001488805,0.000612238,0.0003859242,0.0001388183,0.0003197827,0.01063821,0.0001914829,0.0005705889,0.0158206],"study_design_scores_gemma":[0.00002550937,0.00009091281,0.997789,0.00001450741,0.0001864805,0.0002434735,0.0000885672,0.0005188233,0.0003428254,0.000282259,0.0004134529,0.000004188426],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949328,0.003796017,0.0002313164,0.0001503557,0.00001063351,0.000003250873,0.0004891286,0.00001380905,0.0003726505],"genre_scores_gemma":[0.9987602,0.0003599123,0.0002445879,0.00002119878,0.00001180395,0.000003194012,0.0003565751,0.000003332751,0.0002392108],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003506628,"threshold_uncertainty_score":0.006972432,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02377600977750977,"score_gpt":0.2671916094611973,"score_spread":0.2434155996836875,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}