{"id":"W4312087831","doi":"10.1002/alz.065610","title":"Amyloid and tau‐driven signatures in hippocampal GFAP‐positive astrocytes","year":2022,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Glial fibrillary acidic protein; Astrocyte; Biology; Amyloid precursor protein; Hippocampal formation; Molecular biology; Alzheimer's disease; Cell biology; Neuroscience; Pathology; Immunohistochemistry; Immunology; Disease; Medicine; Central nervous system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001550743,0.000342903,0.000374494,0.001229343,0.0003667481,0.0004949662,0.0001141279,0.0001797602,0.001219295],"category_scores_gemma":[0.0002393646,0.0001040858,0.0004413577,0.001464025,0.000180034,0.0001321191,0.00039046,0.0002525734,0.0005130282],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001772677,"about_ca_system_score_gemma":0.0002984415,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001029057,"about_ca_topic_score_gemma":0.001323671,"domain_scores_codex":[0.9997905,0.00001214314,0.00001499758,0.00007107793,0.00006368425,0.00004762112],"domain_scores_gemma":[0.9998518,0.00002450657,0.0000462315,0.000009880083,0.00004179975,0.0000256658],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007993468,0.00007924585,0.07172063,0.000807016,0.0002508078,0.0005144204,0.0002203132,0.0007231689,0.905866,0.0003622313,0.001124837,0.01753205],"study_design_scores_gemma":[0.00002668485,0.0002958024,0.8513944,0.000088184,0.0003939977,0.002237198,0.0004404993,0.005125531,0.1288122,0.001173687,0.009966688,0.00004509465],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9767638,0.002444125,0.003932386,0.00005452334,0.00002924526,0.00003412062,0.01493135,0.0001560739,0.001654424],"genre_scores_gemma":[0.9701831,0.001381009,0.005181904,0.00008187043,0.00002285224,0.0001041959,0.02124622,0.00004769798,0.001751006],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001229343,"threshold_uncertainty_score":0.004078984,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01814364951751194,"score_gpt":0.2853593222584006,"score_spread":0.2672156727408886,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}