{"id":"W4312093790","doi":"10.3324/haematol.2022.282191","title":"Under the surface: scratching the acute lymphoblastic leukemia niche","year":2022,"lang":"en","type":"letter","venue":"Haematologica","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Scratching; Lymphoblastic Leukemia; Niche; Medicine; Leukemia; Immunology; Biology; Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.001130306,0.0008949143,0.001415325,0.0001521663,0.001527718,0.0002312034,0.002282673,0.001235196,0.004941131],"category_scores_gemma":[0.0005262084,0.0004177546,0.000645081,0.0008854356,0.00110775,0.00007902367,0.00168056,0.007399648,0.001105676],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003530078,"about_ca_system_score_gemma":0.003709194,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000273761,"about_ca_topic_score_gemma":0.0000106698,"domain_scores_codex":[0.9927462,0.001102817,0.0008624981,0.001187845,0.002510155,0.001590436],"domain_scores_gemma":[0.9917027,0.004882054,0.0004734575,0.00256215,0.0002046731,0.0001750052],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002456997,0.000033596,0.00006029098,0.0002037274,0.0009240467,0.01036492,0.0002228387,0.0002463007,0.00007574316,0.0004083537,0.9870956,0.0001188725],"study_design_scores_gemma":[0.00187522,0.0004543446,0.0002664156,0.0001909031,0.001418098,0.01691261,0.0007649461,0.002557816,0.00009983817,0.001347297,0.9734768,0.0006357659],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.02352398,0.001380225,0.0004601695,0.959561,0.001078451,0.002154821,0.0001300185,0.0004093389,0.01130195],"genre_scores_gemma":[0.04013582,0.0005051204,0.0003467512,0.9254231,0.001987343,0.0004568198,0.0005277566,0.0002539922,0.03036328],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.03413793,"threshold_uncertainty_score":0.9998274,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03023946263437365,"score_gpt":0.291282967349312,"score_spread":0.2610435047149383,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}