{"id":"W4312095146","doi":"10.3324/haematol.2022.280482","title":"Adjusted comparison of outcomes between patients from CARTITUDE-1 <i>versus</i> multiple myeloma patients with prior exposure to proteasome inhibitors, immunomodulatory drugs and anti-CD38 antibody from the prospective, multinational LocoMMotion study of real-world clinical practice","year":2022,"lang":"en","type":"article","venue":"Haematologica","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotel Dieu Hospital; Princess Margaret Cancer Centre; University Health Network","funders":"Legend Biotech","keywords":"Medicine; Hazard ratio; Internal medicine; Multiple myeloma; Confidence interval; Dexamethasone; Gastroenterology; Pomalidomide; Cyclophosphamide; Proportional hazards model; Oncology; Bortezomib; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003105519,0.0004679307,0.0008488051,0.0004532047,0.0001413925,0.0005148378,0.0005587731,0.0005343039,0.001699976],"category_scores_gemma":[0.005290041,0.0002730859,0.00161708,0.0005485932,0.0002909248,0.0005082851,0.000621743,0.000914151,0.0000823552],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000413297,"about_ca_system_score_gemma":0.0003717097,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001803697,"about_ca_topic_score_gemma":0.002028833,"domain_scores_codex":[0.9975991,0.001048784,0.0001900784,0.0006901501,0.0002444184,0.0002275876],"domain_scores_gemma":[0.9948949,0.00207765,0.001788342,0.0005949009,0.0001771935,0.000466972],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.1705084,0.0003712078,0.8000129,0.0002424635,0.00867808,0.0002657899,0.0001582097,0.002249288,0.003636392,0.0002478315,0.001382187,0.01224719],"study_design_scores_gemma":[0.00262269,0.01589376,0.9724169,0.00002854693,0.00284405,0.0002822693,0.0001961995,0.003594167,0.0009119912,0.0002083939,0.0009660302,0.00003493846],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982883,0.0003740968,0.0002232947,0.00002944968,0.0000205118,0.00002114072,0.0007559919,0.000005779563,0.0002814659],"genre_scores_gemma":[0.9988161,0.00003982579,0.000103686,0.00003791826,0.00001547231,0.00002940928,0.000829905,0.000003636681,0.0001240195],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003105519,"threshold_uncertainty_score":0.01642376,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03679352061212361,"score_gpt":0.3502240453261489,"score_spread":0.3134305247140253,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}