{"id":"W4312112870","doi":"10.1038/s41541-022-00581-y","title":"A novel intradermal tattoo-based injection device enhances the immunogenicity of plasmid DNA vaccines","year":2022,"lang":"en","type":"article","venue":"npj Vaccines","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre; Université Laval","funders":"Government of Canada; Canadian Institutes of Health Research; Université Laval","keywords":"DNA vaccination; Immunogenicity; Medicine; Immune system; Intradermal injection; Immunology; Virology; Vaccination; Monkeypox; Vaccinia; Biology; Recombinant DNA; Immunization","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002147924,0.0001841419,0.0002907901,0.000142729,0.0004423077,0.00001477189,0.0001367237,0.00005030349,0.0008230711],"category_scores_gemma":[0.00007509253,0.0001268439,0.0001570146,0.0005796116,0.00002523699,0.00008471309,0.00007350674,0.0002394482,0.00001429699],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001045707,"about_ca_system_score_gemma":0.0001599922,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006845049,"about_ca_topic_score_gemma":0.0001812649,"domain_scores_codex":[0.9988431,0.00007650875,0.0003551347,0.0002416929,0.0002649316,0.000218656],"domain_scores_gemma":[0.999142,0.0001676237,0.0001766847,0.0003437129,0.0001201358,0.00004984094],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004476844,0.008938705,0.3156143,0.0005738044,0.002537307,0.00006276558,0.002501437,0.005431555,0.5691976,0.0006651902,0.00616384,0.08383669],"study_design_scores_gemma":[0.01292761,0.003459461,0.3317788,0.0001238592,0.001090257,0.0008639951,0.00177928,0.00382877,0.5821289,0.0001827069,0.06126611,0.0005701853],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962566,0.000364016,0.0003599573,0.001361269,0.0004800531,0.0004418201,0.00004606807,0.00008029228,0.0006099307],"genre_scores_gemma":[0.9984904,0.00002167231,0.000295269,0.0005192781,0.0001529133,0.0001890305,0.00003822517,0.00002366858,0.0002695284],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0832665,"threshold_uncertainty_score":0.9012052,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02067957634598001,"score_gpt":0.2773139550290875,"score_spread":0.2566343786831075,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}