{"id":"W4312113458","doi":"10.1152/ajpheart.00462.2022","title":"Female sex-specific considerations to improve rigor and reproducibility in cardiovascular research","year":2022,"lang":"en","type":"editorial","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Sex and Gender in Healthcare","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Kidney Disease Network; Libin Cardiovascular Institute of Alberta; University of Calgary; University of Alberta","funders":"","keywords":"Generalizability theory; Inclusion and exclusion criteria; Medicine; Disease; Inclusion (mineral); Clinical trial; Health care; Clinical significance; Cardiovascular health; Gerontology; Alternative medicine; Psychology; Internal medicine; Pathology; Developmental psychology; Social psychology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[{"model":"gemma","categories":["metaresearch"],"domain":"reproducibility","study_design":"not_applicable","genre":"editorial","about_ca_system":false,"about_ca_topic":false,"confidence":"low","status":"direct model label, unvalidated"},{"model":"gpt","categories":["metaresearch"],"domain":"reproducibility","study_design":"not_applicable","genre":"editorial","about_ca_system":false,"about_ca_topic":false,"confidence":"high","status":"direct model label, unvalidated"}],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.006377296,0.0003829523,0.00242269,0.0006264208,0.0003533795,0.00001895726,0.0001934543,0.0004011687,0.0001348752],"category_scores_gemma":[0.001932049,0.0003508073,0.0003993214,0.0005081375,0.001357885,0.00007367288,0.0003108369,0.003344938,0.000006681071],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002942644,"about_ca_system_score_gemma":0.001193368,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003750753,"about_ca_topic_score_gemma":0.00001444064,"domain_scores_codex":[0.9928294,0.002201077,0.001012291,0.002473369,0.000778352,0.0007054883],"domain_scores_gemma":[0.9942334,0.001790185,0.0003303427,0.00238779,0.0008289072,0.0004294232],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008331444,0.0002895168,0.001765396,0.0004748702,0.0008000109,0.00002288696,0.002737736,0.00007425829,0.804162,0.00003526007,0.185695,0.003109944],"study_design_scores_gemma":[0.001411139,0.004306349,0.3652264,0.00009309766,0.0001296793,0.0002516408,0.005153672,0.000005343488,0.0002493332,0.001782164,0.621013,0.0003781918],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8822037,0.009544159,2.194347e-7,0.0005085477,0.1069325,0.0007012581,0.00006637069,0.00001533118,0.00002790619],"genre_scores_gemma":[0.8467051,0.001097532,0.0001716317,0.0004738678,0.1513146,0.00007986473,0.00005172456,0.00005699572,0.0000487346],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8039126,"threshold_uncertainty_score":0.9998944,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05806382055516209,"score_gpt":0.3561181826125531,"score_spread":0.2980543620573911,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}