{"id":"W4312115002","doi":"10.1182/blood.2022017147","title":"Novel insights into Hodgkin lymphoma biology by single-cell analysis","year":2022,"lang":"en","type":"article","venue":"Blood","topic":"Single-cell and spatial transcriptomics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Spinal Cord Injury BC; University of British Columbia","funders":"","keywords":"Tumor microenvironment; Biology; Computational biology; Immunotherapy; Immune system; Single-cell analysis; Systems biology; Lymphoma; Cell; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001076824,0.0005375799,0.0007918344,0.001721128,0.0002116356,0.001283154,0.000523763,0.0007554276,0.0007914018],"category_scores_gemma":[0.0006543797,0.0002827561,0.000450906,0.0006645116,0.0006306454,0.001746987,0.0005881453,0.001260749,0.0005182215],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007213926,"about_ca_system_score_gemma":0.0004014066,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000422778,"about_ca_topic_score_gemma":0.0007658303,"domain_scores_codex":[0.9996572,0.00007264188,0.00003268164,0.00008967835,0.0001167401,0.00003106276],"domain_scores_gemma":[0.999712,0.0001179058,0.00003363613,0.00002298197,0.00007875323,0.00003462848],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000247623,0.00008905328,0.007482761,0.004416377,0.0001438759,0.001471596,0.0005941459,0.001665842,0.5903226,0.01859088,0.009830395,0.3651448],"study_design_scores_gemma":[0.00006410851,0.0007343922,0.02638224,0.001365723,0.0004406889,0.009572551,0.00108345,0.01982928,0.2854735,0.04108232,0.6137322,0.0002395612],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.043049,0.8356985,0.1077216,0.003691544,0.001007919,0.0001249199,0.0009184668,0.0006888407,0.007099177],"genre_scores_gemma":[0.2103087,0.6873019,0.0908801,0.002796702,0.002245432,0.000221938,0.001252075,0.0001027051,0.004890409],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.001721128,"threshold_uncertainty_score":0.005694807,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009523246311929153,"score_gpt":0.2057959706925294,"score_spread":0.1962727243806002,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}