{"id":"W4312121913","doi":"10.21203/rs.3.rs-2327706/v1","title":"The Caenorhabditis elegans Shugoshin regulates TAC-1 in cilia","year":2022,"lang":"en","type":"preprint","venue":"Research Square","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute; University of British Columbia; Simon Fraser University; University of Saskatchewan","funders":"","keywords":"Cell biology; Kinetochore; Biology; Centriole; Centrosome; Caenorhabditis elegans; Cilium; Basal body; Centrosome cycle; Chromosome segregation; Microtubule; Spindle pole body; Cohesin; Spindle apparatus; Genetics; Meiosis; Cell division; Cell cycle; Chromosome; Cell; Flagellum; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004701229,0.0003396687,0.0001056619,0.0002137669,0.0003555239,0.0002095174,0.0001870906,0.0002600731,0.001165408],"category_scores_gemma":[0.0000682168,0.0001321629,0.0001653764,0.00005520882,0.0002208469,0.0001174295,0.0002982845,0.0002528091,0.0005143486],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000534244,"about_ca_system_score_gemma":0.0001891035,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002561794,"about_ca_topic_score_gemma":0.006347424,"domain_scores_codex":[0.9999449,0.00000277414,0.00000242894,0.00001958094,0.00001570381,0.00001464245],"domain_scores_gemma":[0.9999139,0.000008851038,0.00002446375,0.000006789745,0.00001392987,0.00003201279],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003339711,0.000005555615,0.0003401023,0.00001896545,0.000001389755,0.00007325909,0.000009854896,0.0000476856,0.9986392,0.00008084835,0.00007730393,0.0006723889],"study_design_scores_gemma":[0.00002751185,0.0001229134,0.07341411,0.00003047632,0.00002274084,0.0003476857,0.0001051546,0.004945635,0.9146748,0.0002228888,0.006073565,0.0000124467],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950826,0.0008224143,0.001481175,0.00007805316,0.00002901035,0.000009687244,0.0002229297,0.0001384159,0.002135551],"genre_scores_gemma":[0.9956635,0.0001858766,0.0006775949,0.00002824777,0.000002853759,0.000008083449,0.000274507,0.00002171755,0.003137661],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002561794,"threshold_uncertainty_score":0.005093813,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02397218000207216,"score_gpt":0.3491931660314762,"score_spread":0.3252209860294041,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}