{"id":"W4312140626","doi":"10.1016/j.humpath.2022.12.006","title":"Cathepsin protease expression in infiltrative soft tissue sarcomas: cathepsin-K correlates with infiltrative tumor growth and clinical outcomes","year":2022,"lang":"en","type":"article","venue":"Human Pathology","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Mount Sinai Hospital","funders":"National Cancer Institute; National Institutes of Health; Japan Society for the Promotion of Science; Yasuda Memorial Medical Foundation","keywords":"Cathepsin H; Immunohistochemistry; Cathepsin D; Cathepsin B; Pathology; Cathepsin L; Cathepsin; Biology; Cancer research; Medicine; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003077008,0.0001935583,0.0002382812,0.0005843992,0.0001556052,0.0005567627,0.0001468489,0.0002681748,0.001444657],"category_scores_gemma":[0.0008714042,0.0001063261,0.0001372719,0.0005392329,0.0003052846,0.0003027655,0.0002952187,0.0002697594,0.0003055248],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001472209,"about_ca_system_score_gemma":0.0001509673,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003839574,"about_ca_topic_score_gemma":0.0004740615,"domain_scores_codex":[0.9998481,0.00003017105,0.0000195998,0.0000308623,0.0000341383,0.00003723133],"domain_scores_gemma":[0.9989654,0.0001611861,0.0005469706,0.00005583043,0.00008950969,0.0001810356],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007402459,0.00003481642,0.9635823,0.0000198112,0.00003179436,0.0003370717,0.00008973498,0.000077303,0.03167043,0.00004451818,0.00003557459,0.003336346],"study_design_scores_gemma":[0.000004227623,0.0001623191,0.9943288,0.000003899973,0.00002832685,0.001693978,0.0001849309,0.0002075632,0.003082903,0.0000566513,0.0002423528,0.000004118961],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992988,0.0001893648,0.0001084789,0.0000110094,0.000001584975,0.000001994974,0.00005835003,0.000004247575,0.0003262452],"genre_scores_gemma":[0.9996295,0.00007895526,0.00005066967,0.00000377967,0.00000380942,0.000001821418,0.0000725579,0.000001435166,0.0001573611],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001444657,"threshold_uncertainty_score":0.004832923,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01474769696953606,"score_gpt":0.2878022806311142,"score_spread":0.2730545836615782,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}