{"id":"W4312171479","doi":"10.3390/toxics11010013","title":"Effects of Melanized Bacteria and Soluble Melanin on the Intestinal Homeostasis and Microbiome In Vivo","year":2022,"lang":"en","type":"article","venue":"Toxics","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Congressionally Directed Medical Research Programs; Office of Naval Research; Canadian Space Agency; National Institutes of Health; U.S. Department of Veterans Affairs; U.S. Navy; Crohn's and Colitis Foundation; National Institute of Diabetes and Digestive and Kidney Diseases; U.S. Department of Defense","keywords":"Microbiology; Dysbiosis; Microbiome; Bacteria; Melanin; Biology; Colonization; Gut flora; Inflammation; Probiotic; Intestinal mucosa; Immunology; Biochemistry; Medicine; Bioinformatics; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001938452,0.00007807471,0.0001105203,0.00003542958,0.00007621772,0.000008268637,0.00008063131,0.00003824282,0.00004039034],"category_scores_gemma":[0.00003408141,0.00006272556,0.00001694609,0.00006979197,0.00005382884,0.000001075451,0.0001751757,0.00009334554,6.10857e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001147548,"about_ca_system_score_gemma":0.00003282116,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003897464,"about_ca_topic_score_gemma":0.00002611554,"domain_scores_codex":[0.9994722,0.00009180747,0.0001093169,0.000155997,0.00003863276,0.0001320195],"domain_scores_gemma":[0.999754,0.00004471882,0.00004827089,0.0001136079,0.00001050441,0.00002893345],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001014835,0.00004795315,0.0005584375,0.00004675051,0.000009120881,0.000002765094,0.0001519638,7.548678e-7,0.9971709,0.0001179148,0.001449592,0.0003423144],"study_design_scores_gemma":[0.0009433645,0.0007273507,0.01103229,0.00002206158,0.00001044139,0.00005123215,0.0001521652,0.000009021735,0.974687,0.00004967804,0.01220206,0.0001132816],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983979,0.0008604282,0.000007205276,0.0003971467,0.00006139493,0.0001714134,0.00002521732,0.000002877658,0.00007644219],"genre_scores_gemma":[0.99896,0.000242561,0.0001962975,0.0004062771,0.00001482483,0.00001274384,0.00001410873,0.000009396626,0.0001438603],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02248389,"threshold_uncertainty_score":0.2557874,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006717852278819355,"score_gpt":0.2222524486456862,"score_spread":0.2155345963668669,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}