{"id":"W4312171479","doi":"10.3390/toxics11010013","title":"Effects of Melanized Bacteria and Soluble Melanin on the Intestinal Homeostasis and Microbiome In Vivo","year":2022,"lang":"en","type":"article","venue":"Toxics","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Congressionally Directed Medical Research Programs; Office of Naval Research; Canadian Space Agency; National Institutes of Health; U.S. Department of Veterans Affairs; U.S. Navy; Crohn's and Colitis Foundation; National Institute of Diabetes and Digestive and Kidney Diseases; U.S. Department of Defense","keywords":"Microbiology; Dysbiosis; Microbiome; Bacteria; Melanin; Biology; Colonization; Gut flora; Inflammation; Probiotic; Intestinal mucosa; Immunology; Biochemistry; Medicine; Bioinformatics; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001261119,0.0002266151,0.0001713433,0.0001236863,0.00008866726,0.0001487253,0.00006575438,0.0002293617,0.001024488],"category_scores_gemma":[0.0001256594,0.00007987484,0.0001627136,0.00006169165,0.0001883747,0.0001508315,0.000166457,0.0003721588,0.0001094714],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008580954,"about_ca_system_score_gemma":0.0001390037,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003159539,"about_ca_topic_score_gemma":0.000564403,"domain_scores_codex":[0.9999079,0.00002716016,0.000005675493,0.00001797838,0.00001841961,0.00002278561],"domain_scores_gemma":[0.9999031,0.00001664561,0.00002441373,0.00001099214,0.00001018551,0.00003469686],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004803605,0.00007472639,0.0002610918,0.00002544502,0.00000484828,0.00001785503,0.00001637892,0.00003401013,0.9979864,0.00002018876,0.00001090816,0.001067656],"study_design_scores_gemma":[0.00003188001,0.003943121,0.01185847,0.00001459394,0.00002213891,0.0001011152,0.00007251729,0.0006496217,0.9818771,0.00006326319,0.001359482,0.000006801881],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978178,0.000714705,0.0006839947,0.00005751006,0.0000171385,0.0000184269,0.0001234827,0.00001370258,0.0005533514],"genre_scores_gemma":[0.9958298,0.0006161658,0.00138677,0.00006633648,0.000009872392,0.00003644787,0.0001891813,0.00001026897,0.001855216],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001024488,"threshold_uncertainty_score":0.003427267,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006717852278819355,"score_gpt":0.2222524486456862,"score_spread":0.2155345963668669,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}