{"id":"W4312196592","doi":"10.3390/cells11244131","title":"Redox Genetic Risk Score and the Incidence of End-Stage Kidney Disease in People with Type 1 Diabetes","year":2022,"lang":"en","type":"article","venue":"Cells","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hamilton Health Sciences; McMaster University; Population Health Research Institute","funders":"","keywords":"Type 2 diabetes; Diabetes mellitus; Incidence (geometry); Medicine; Kidney disease; Disease; End stage renal disease; Internal medicine; Bioinformatics; End-stage kidney disease; Endocrinology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001238271,0.0003184565,0.000353875,0.0007782644,0.0003082749,0.0006858704,0.0002872331,0.0005826198,0.001147743],"category_scores_gemma":[0.003859455,0.0002326804,0.0007742735,0.0008389934,0.0001966205,0.0002606831,0.0005026013,0.0008842474,0.0001554994],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001918071,"about_ca_system_score_gemma":0.000181793,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003547894,"about_ca_topic_score_gemma":0.002908711,"domain_scores_codex":[0.9995833,0.0001618077,0.00003522096,0.00008890866,0.00008677698,0.00004398537],"domain_scores_gemma":[0.9984431,0.0003734228,0.0005979199,0.0001849448,0.0001580345,0.0002425912],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002598047,0.00002752412,0.9983166,0.000005811181,0.0001242792,0.00002660209,0.00001893524,0.0000483026,0.0001442723,0.00001335854,0.0000427209,0.0009716924],"study_design_scores_gemma":[0.00001396782,0.0001272353,0.9989636,0.0000039883,0.0001308327,0.0001111892,0.00003015223,0.0004194009,0.00006213735,0.00005614953,0.00007749167,0.000003872168],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988512,0.0002773832,0.0001773959,0.00007241752,0.000012708,0.000005425484,0.0002578476,0.000007609615,0.0003380787],"genre_scores_gemma":[0.99931,0.00009689273,0.0002117537,0.00002887221,0.00001652571,0.000004395705,0.0001943319,0.000001784339,0.0001353317],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003547894,"threshold_uncertainty_score":0.007054508,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006397932283843987,"score_gpt":0.2418407345967002,"score_spread":0.2354428023128562,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}