{"id":"W4312196592","doi":"10.3390/cells11244131","title":"Redox Genetic Risk Score and the Incidence of End-Stage Kidney Disease in People with Type 1 Diabetes","year":2022,"lang":"en","type":"article","venue":"Cells","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hamilton Health Sciences; McMaster University; Population Health Research Institute","funders":"","keywords":"Type 2 diabetes; Diabetes mellitus; Incidence (geometry); Medicine; Kidney disease; Disease; End stage renal disease; Internal medicine; Bioinformatics; End-stage kidney disease; Endocrinology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002019358,0.00005702659,0.0000732922,0.00002494881,0.00006659172,0.000005425541,0.0001467472,0.00001247842,0.0001064244],"category_scores_gemma":[0.0001936605,0.0000414384,0.00001258257,0.0001666274,0.0001532207,0.000002156437,0.0001944568,0.00009346823,0.000001237384],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008124209,"about_ca_system_score_gemma":0.0001444314,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004251617,"about_ca_topic_score_gemma":0.00002083393,"domain_scores_codex":[0.9993252,0.0001384625,0.00009033346,0.0001989119,0.0001277756,0.0001193071],"domain_scores_gemma":[0.9994997,0.00002959958,0.0000578701,0.000305446,0.00004333071,0.00006399721],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001126291,0.00009823615,0.5425047,0.000140719,0.00003727308,0.000008715409,0.0005326266,0.01566,0.436213,0.0001018489,0.00127798,0.002298693],"study_design_scores_gemma":[0.003594311,0.0008561547,0.2721077,0.00003688351,0.0000555296,0.000004252963,0.0004480885,0.001998485,0.6436837,0.0007567785,0.07599511,0.0004630478],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970363,0.002349257,0.00005641832,0.0001582022,0.00003186559,0.0002136484,0.0000702715,0.000002088387,0.00008195127],"genre_scores_gemma":[0.9977778,0.0007883695,0.0002814217,0.00011017,0.00002113011,0.00003708302,0.00004559738,0.000009459576,0.0009289288],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.270397,"threshold_uncertainty_score":0.1689809,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006397932283843987,"score_gpt":0.2418407345967002,"score_spread":0.2354428023128562,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}