{"id":"W4312205397","doi":"10.1101/2022.12.12.520021","title":"SARS-CoV-2 vaccine-breakthrough infections (VBIs) by Omicron (B.1.1.529) variant and consequences in structural and functional impact","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Umm Al-Qura University","keywords":"Infectivity; Mutagenesis; Virology; Mutation; Mutant; Virus; Biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000132355,0.0002113317,0.0001611091,0.00007486621,0.0001521601,0.0001537668,0.0002197603,0.0002108629,0.001227968],"category_scores_gemma":[0.0001186674,0.00007706824,0.0002237167,0.0000727221,0.000126314,0.0001055281,0.0001247398,0.0002308124,0.0001824353],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005420385,"about_ca_system_score_gemma":0.0001391093,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003028032,"about_ca_topic_score_gemma":0.00361409,"domain_scores_codex":[0.9999359,0.00001190114,0.000003135855,0.00001197469,0.00001823305,0.00001889985],"domain_scores_gemma":[0.9999691,0.000007615823,0.000009447019,0.000002903537,0.000003388844,0.00000765129],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001440277,0.0004259567,0.03233938,0.00005440139,0.00007224561,0.000678695,0.00007477502,0.004664083,0.9520992,0.0007945828,0.0002715741,0.007084775],"study_design_scores_gemma":[0.0005104152,0.007576122,0.2281713,0.00004626178,0.0001681347,0.006498435,0.0004474134,0.05910266,0.6897793,0.001091143,0.006550852,0.00005793696],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993268,0.00007411273,0.000167755,0.0000157485,0.00000261798,0.000003303282,0.00004211029,0.000004434905,0.0003631266],"genre_scores_gemma":[0.9994577,0.00002822171,0.0002795397,0.0000134267,0.000001204976,0.000001906202,0.00008889375,0.000002520058,0.0001266194],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003028032,"threshold_uncertainty_score":0.006020844,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0272834064590465,"score_gpt":0.3059651656426791,"score_spread":0.2786817591836326,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}