{"id":"W4312209891","doi":"10.3390/metabo12121284","title":"Cancer Cachexia and Dysregulated Phosphate Metabolism: Insights from Mutant p53 and Mutant Klotho Mouse Models","year":2022,"lang":"en","type":"article","venue":"Metabolites","topic":"Parathyroid Disorders and Treatments","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"","keywords":"Cachexia; Klotho; Carcinogenesis; Biology; Cancer; Cancer research; Wasting; Anabolism; Endocrinology; Internal medicine; Medicine; Kidney; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003645491,0.001075082,0.0005784754,0.001467526,0.0003072195,0.0005136293,0.0005137047,0.0007708825,0.001069719],"category_scores_gemma":[0.0001634184,0.0002737128,0.0004575555,0.0003688369,0.000704108,0.0006124069,0.0004946009,0.001043641,0.000183057],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004208786,"about_ca_system_score_gemma":0.000337275,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004812328,"about_ca_topic_score_gemma":0.001188951,"domain_scores_codex":[0.9998558,0.00002829954,0.00001452274,0.00003136694,0.00004767708,0.00002236616],"domain_scores_gemma":[0.9998547,0.00002452645,0.00005536047,0.00001452834,0.00001133839,0.00003963274],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009757536,0.0003510876,0.002222309,0.000340628,0.00006260839,0.001860553,0.0001140256,0.0003223328,0.9767593,0.004076301,0.0005112846,0.01240383],"study_design_scores_gemma":[0.0005801111,0.005671504,0.03144228,0.0003734194,0.0007936796,0.02326709,0.0005713951,0.008473359,0.864441,0.0103464,0.05390615,0.0001336888],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9330533,0.02481653,0.03104252,0.003029829,0.0002377566,0.0001341779,0.000975966,0.0005058021,0.006204151],"genre_scores_gemma":[0.9430194,0.03392965,0.01504941,0.0005788152,0.0001261423,0.0001864383,0.001002826,0.00008208375,0.006025173],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001467526,"threshold_uncertainty_score":0.003578603,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01681712642242308,"score_gpt":0.2523710729292239,"score_spread":0.2355539465068009,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}