{"id":"W4312222022","doi":"10.1016/j.bbrc.2022.12.073","title":"Comparative changes in breast cancer cell proliferation and signalling following somatostatin and cannabidiol treatment","year":2022,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Neuroendocrine Tumor Research Advances","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia Hospital; University of British Columbia","funders":"Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta; Faculty of Pharmaceutical Sciences, University of British Columbia; Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; University of British Columbia","keywords":"Cancer research; PI3K/AKT/mTOR pathway; Cell growth; Signal transduction; Protein kinase B; Apoptosis; Somatostatin receptor; Biology; Cancer cell; Somatostatin; Cancer; Cell biology; Endocrinology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001765774,0.0001796199,0.0005737974,0.0004346879,0.0003642746,0.0004684719,0.0002327394,0.000541374,0.003982964],"category_scores_gemma":[0.0003481683,0.0001667305,0.0004390307,0.0005966068,0.0003826556,0.000399164,0.0001676884,0.0008984233,0.0007447437],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005349789,"about_ca_system_score_gemma":0.0004723057,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003616103,"about_ca_topic_score_gemma":0.004290772,"domain_scores_codex":[0.9996608,0.00004354418,0.00002248086,0.00003295072,0.00007274676,0.000167385],"domain_scores_gemma":[0.9997284,0.0000959749,0.00002272811,0.00002968466,0.00004658514,0.00007661265],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.008782152,0.0004175876,0.001010373,0.00008785694,0.000030933,0.000310612,0.0001743464,0.0001750375,0.9824277,0.0002244642,0.0003573945,0.006001494],"study_design_scores_gemma":[0.0001462888,0.003564307,0.05045136,0.00001202681,0.00007249355,0.000388135,0.0009174817,0.0008104176,0.938951,0.0001680032,0.004489378,0.00002899163],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942495,0.001402733,0.0002354925,0.0001482402,0.00009663762,0.00001607723,0.0007165616,0.00002821858,0.003106666],"genre_scores_gemma":[0.9925565,0.000842021,0.000280741,0.00008914187,0.00002632361,0.00004990901,0.0008911187,0.00001108848,0.005253308],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003982964,"threshold_uncertainty_score":0.01332432,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09302161828376938,"score_gpt":0.4181961561605033,"score_spread":0.3251745378767339,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}