{"id":"W4312329817","doi":"10.2139/ssrn.4284067","title":"Schlafen-5 Inhibits LINE-1 Retrotransposition","year":2022,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Retrotransposon; Line (geometry); Biology; Computer science; Genetics; Mathematics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001913503,0.0004401804,0.0003529679,0.0004516082,0.0002645517,0.0004677871,0.0004969978,0.0005464632,0.005366452],"category_scores_gemma":[0.0002553599,0.0001928995,0.0003281419,0.0002562365,0.0003938952,0.0002232705,0.0002840962,0.001091556,0.001106595],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004642015,"about_ca_system_score_gemma":0.0004812883,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009695959,"about_ca_topic_score_gemma":0.001961374,"domain_scores_codex":[0.9997677,0.0000423859,0.00002729605,0.00003474275,0.00005159621,0.00007630896],"domain_scores_gemma":[0.9997796,0.00008610643,0.00003630705,0.0000275349,0.000007977534,0.00006242383],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001318623,0.0003960209,0.000367047,0.00006239397,0.00003059511,0.0001457663,0.00003558418,0.0002687287,0.9914804,0.0003385913,0.0005238524,0.005032423],"study_design_scores_gemma":[0.0001841939,0.0015959,0.002298669,0.000007178596,0.0000263805,0.0001995969,0.00003431588,0.0009602148,0.9915835,0.00007939916,0.00302111,0.00000949313],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913337,0.001094718,0.001209487,0.0003244539,0.000151813,0.00005441127,0.0009822007,0.0003209131,0.004528307],"genre_scores_gemma":[0.9928809,0.0004933782,0.001021053,0.0001062604,0.00003137124,0.0000413708,0.00156983,0.00003244891,0.003823243],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005366452,"threshold_uncertainty_score":0.01795256,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007634514650239479,"score_gpt":0.2262430505493192,"score_spread":0.2186085358990797,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}