{"id":"W4312532285","doi":"10.20517/jtgg.2022.07","title":"Genetic risk and its role in primary prevention of CAD","year":2022,"lang":"en","type":"article","venue":"Journal of Translational Genetics and Genomics","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian HIV Trials Network, Canadian Institutes of Health Research; Canada Foundation for Innovation","keywords":"Medicine; Coronary artery disease; Statin; Disease; Risk assessment; Genetic predisposition; Genetic testing; Internal medicine; Bioinformatics; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002551923,0.0004088136,0.0006788675,0.0008220013,0.0004712633,0.001966292,0.0004451586,0.001441916,0.003371334],"category_scores_gemma":[0.008088124,0.0001856299,0.0004867808,0.0008683317,0.001148839,0.000770273,0.0007407241,0.002216819,0.0006075783],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008803827,"about_ca_system_score_gemma":0.001303527,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003537629,"about_ca_topic_score_gemma":0.002587125,"domain_scores_codex":[0.9982557,0.001038523,0.0000793685,0.0002055463,0.0003323024,0.00008861259],"domain_scores_gemma":[0.9968532,0.001627036,0.0005393219,0.0001757352,0.0003838637,0.0004209486],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0007959839,0.0006672313,0.2542261,0.001272029,0.001327602,0.0007190531,0.0008149355,0.001655955,0.001763144,0.07781485,0.03196589,0.6269772],"study_design_scores_gemma":[0.0001907582,0.001315464,0.5604646,0.004488834,0.001753396,0.003629477,0.0009690291,0.004888652,0.001188901,0.2088404,0.2120613,0.0002091722],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.1048959,0.6201852,0.01064505,0.2126515,0.004213871,0.00008022952,0.0007282553,0.0001642034,0.0464357],"genre_scores_gemma":[0.6765462,0.2871853,0.008352615,0.01369691,0.007850021,0.00006352277,0.000320203,0.00003518756,0.005950117],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.003537629,"threshold_uncertainty_score":0.01349604,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00868713260298497,"score_gpt":0.2360171346549026,"score_spread":0.2273300020519176,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}