{"id":"W4312602647","doi":"10.56431/p-ft6gk2","title":"Synthesis and Antimicrobial Screening 6-Aryl-2-(Amino/Methoxy)-4-[(4′-Difluoro Methoxy) (3′-Hydroxy) Phenyl] Nicotinonitrile","year":2015,"lang":"en","type":"article","venue":"International Letters of Chemistry Physics and Astronomy","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Occupational and Environmental Medical Association of Canada","funders":"Saurashtra University","keywords":"Malononitrile; Chalcone; Ammonium acetate; Sodium methoxide; Chemistry; Antimicrobial; Aryl; Medicinal chemistry; Methanol; Organic chemistry; Combinatorial chemistry; Catalysis; High-performance liquid chromatography","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001339355,0.0006030563,0.0004680688,0.0004717615,0.0001953645,0.0001708137,0.0003184747,0.000234985,0.001526868],"category_scores_gemma":[0.0001495823,0.0001440298,0.0002298058,0.0003568835,0.0001364815,0.0002019087,0.0001633734,0.0002625308,0.0005296688],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001641435,"about_ca_system_score_gemma":0.0002339136,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003995161,"about_ca_topic_score_gemma":0.001115484,"domain_scores_codex":[0.9998831,0.00001947628,0.000014488,0.00002473739,0.00003838413,0.00001984756],"domain_scores_gemma":[0.9999032,0.000006690384,0.0000243819,0.0000110364,0.00002993042,0.00002476485],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008243365,0.00005542314,0.0001605321,0.0002901507,0.000008381843,0.0001828989,0.0000211395,0.0002250695,0.9926581,0.000132212,0.00008493342,0.006098672],"study_design_scores_gemma":[0.00002769086,0.001069717,0.001818597,0.00002154905,0.00002924016,0.0004859423,0.0000265681,0.0002864706,0.9883663,0.00004665706,0.007807179,0.00001402749],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9366785,0.02890008,0.01947562,0.0002347797,0.0001742251,0.0007470818,0.002731698,0.000396572,0.01066149],"genre_scores_gemma":[0.9566408,0.0127726,0.02255956,0.00007932357,0.00004598985,0.0002210536,0.001571829,0.00003115719,0.006077694],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001526868,"threshold_uncertainty_score":0.00510788,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02276001596394262,"score_gpt":0.2346552053584874,"score_spread":0.2118951893945447,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}