{"id":"W4313017332","doi":"10.1161/atvb.42.suppl_1.190","title":"Abstract 190: Deletion Of Shp-1 Prevents Diabetes-induced Endothelial Cell Senescence And Restores Blood Flow Reperfusion Following Ischemia","year":2022,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Atherosclerosis and Cardiovascular Diseases","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Internal medicine; Endocrinology; Ischemia; Diabetes mellitus; Medicine; Blood flow; Senescence; Ligation; Hypoxia (environmental); Vascular endothelial growth factor; Chemistry; Oxygen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001071572,0.0003894293,0.0002551341,0.0002492803,0.000128016,0.0001940338,0.0002415131,0.000254052,0.002341229],"category_scores_gemma":[0.0000702187,0.0001297376,0.0002500342,0.0001307102,0.0002164518,0.0001567456,0.0001570685,0.0006502771,0.0005717307],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001942447,"about_ca_system_score_gemma":0.000155908,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003519209,"about_ca_topic_score_gemma":0.0002737237,"domain_scores_codex":[0.999915,0.000009308074,0.00001141963,0.00001910931,0.00001739189,0.00002767078],"domain_scores_gemma":[0.9998502,0.00001570724,0.00005623303,0.00001271174,0.00001041822,0.00005474035],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002929926,0.00008422894,0.0001773971,0.00003747069,0.000004664204,0.000037602,0.000006312148,0.00002879182,0.9983224,0.0000377148,0.00006626752,0.0009041679],"study_design_scores_gemma":[0.00009332632,0.001066132,0.007232631,0.00001258457,0.00002902582,0.0002763428,0.00001917652,0.000475675,0.9886779,0.0000400202,0.002072705,0.000004455913],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961064,0.000759032,0.001269267,0.00009060883,0.00004236614,0.0000207632,0.0007803373,0.0000922621,0.0008388532],"genre_scores_gemma":[0.9915397,0.0007398552,0.001345898,0.00008903287,0.00002657786,0.00006812249,0.001852841,0.00003589019,0.004302084],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002341229,"threshold_uncertainty_score":0.007832229,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0159463855850769,"score_gpt":0.2281357669273787,"score_spread":0.2121893813423018,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}