{"id":"W4313020967","doi":"10.33590/emjoncol/10311156","title":"A Review of Gene Expression Profiling in Early-Stage ER+/HER2- Breast Cancer With A Focus on The PAM50 Risk of Recurrence Assay","year":2019,"lang":"en","type":"review","venue":"EMJ Oncology","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital; Western University","funders":"","keywords":"Breast cancer; Medicine; Oncology; Internal medicine; Adjuvant; Stage (stratigraphy); Adjuvant therapy; Cancer; Gynecology; Bioinformatics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006394633,0.0004146374,0.001706431,0.00007055571,0.00003808629,0.000003131925,0.0003828757,0.000346193,0.00004755716],"category_scores_gemma":[0.0001271657,0.0002281402,0.000282513,0.0002479075,0.0001853966,0.000002882077,0.0001761969,0.0003756528,0.000007298037],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001529484,"about_ca_system_score_gemma":0.0008316941,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004418131,"about_ca_topic_score_gemma":0.0002507754,"domain_scores_codex":[0.9973662,0.0009357546,0.0006350518,0.0005919056,0.0001821853,0.0002888898],"domain_scores_gemma":[0.9975897,0.0002399231,0.001249484,0.0007241472,0.0001573482,0.00003936119],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005169565,0.0005085925,0.002080642,0.05506189,0.001040785,0.00005835885,0.0001430989,0.000006987457,0.0001269766,0.00004273208,0.001448597,0.9389644],"study_design_scores_gemma":[0.001763923,0.002009674,0.00172522,0.2506637,0.002409893,0.0003633196,0.00006682063,0.000001059567,0.006085804,0.00001366284,0.7340415,0.0008554269],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000577382,0.9961247,0.00001906639,0.0001692009,0.0001494013,0.001597727,0.0008257927,0.000004514195,0.0005321589],"genre_scores_gemma":[0.0009250314,0.997321,0.0003308981,0.00009051514,0.0001252766,0.000996214,0.00009155185,0.00004396449,0.00007562112],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.938109,"threshold_uncertainty_score":0.9303288,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03790187487990319,"score_gpt":0.3554090792194852,"score_spread":0.317507204339582,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}