{"id":"W4313119801","doi":"10.1093/bjs/znac242.082","title":"O082 Patient derived renal cell carcinoma tumouroids for personalised renal cancer medicine","year":2022,"lang":"en","type":"article","venue":"British journal of surgery","topic":"Renal cell carcinoma treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"Pazopanib; Medicine; Renal cell carcinoma; Stromal cell; Cancer research; Cabozantinib; Cancer; Kidney cancer; Pathology; Sunitinib; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004296094,0.00028032,0.0005445952,0.0003224777,0.0002519868,0.0008087831,0.0003318473,0.0006118261,0.004497],"category_scores_gemma":[0.000394206,0.0001904068,0.0004981062,0.0002865228,0.0001961194,0.0003616032,0.0005506662,0.0007987379,0.002215064],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004173227,"about_ca_system_score_gemma":0.0003507008,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001116511,"about_ca_topic_score_gemma":0.001804137,"domain_scores_codex":[0.9997022,0.00004595338,0.00002150881,0.00006374766,0.0001299469,0.00003678463],"domain_scores_gemma":[0.9997281,0.00004676194,0.00003614799,0.00006545024,0.00006655991,0.00005706941],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006204208,0.0001522339,0.002418881,0.0005358997,0.00005426804,0.0008749878,0.0002497711,0.001406459,0.963911,0.0005941462,0.003245752,0.02593628],"study_design_scores_gemma":[0.0001001482,0.001240269,0.01238161,0.0001053252,0.0001421969,0.006463825,0.0002996018,0.005840117,0.8735095,0.000481746,0.09937877,0.00005682359],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8888375,0.01840906,0.06426881,0.001293806,0.0006011161,0.0008666128,0.00710966,0.001784072,0.01682934],"genre_scores_gemma":[0.9570482,0.00421882,0.02340609,0.0003321325,0.00003882487,0.0004189405,0.004936557,0.0001461932,0.009454175],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004497,"threshold_uncertainty_score":0.01504391,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04223756148401794,"score_gpt":0.2562993806855718,"score_spread":0.2140618192015539,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}