{"id":"W4313122926","doi":"10.2139/ssrn.4239119","title":"Distal Extracellular Teneurin Region (Teneurin C-Terminal Associated Peptide; TCAP) Possesses Independent Intracellular Calcium Regulating Actions, in Vitro: A Novel Antagonist of Corticotropin-Releasing Factor (CRF)","year":2022,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Extracellular; Antagonist; In vitro; Intracellular; Calcium in biology; Peptide; Cell biology; Corticotropin-releasing hormone; Calcium; Chemistry; Biology; Internal medicine; Receptor; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001865048,0.0003750075,0.0002792328,0.000131058,0.0001794973,0.0002064998,0.0002776429,0.0002023786,0.00172402],"category_scores_gemma":[0.0001934257,0.0001262111,0.0001874017,0.0001250207,0.0001712355,0.0001258254,0.0001736888,0.0005826109,0.0003794124],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002149968,"about_ca_system_score_gemma":0.000412047,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001086027,"about_ca_topic_score_gemma":0.002133436,"domain_scores_codex":[0.9999243,0.00001372761,0.000006383334,0.00001445964,0.00001650987,0.00002446263],"domain_scores_gemma":[0.9999206,0.00002384629,0.000009368381,0.000006599128,0.000008510329,0.00003109128],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003851307,0.00002321106,0.0000627758,0.00002826326,0.000004030452,0.00009729557,0.000007862328,0.00003425054,0.9982637,0.00005456434,0.00003880118,0.001000128],"study_design_scores_gemma":[0.000142735,0.001047016,0.004143376,0.00000815628,0.00004886768,0.001429201,0.00003185393,0.001311433,0.9872497,0.00007754096,0.004502662,0.000007469023],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.98992,0.002494946,0.002440906,0.0001311288,0.00009709175,0.00005022117,0.0003928352,0.00003955571,0.004433318],"genre_scores_gemma":[0.9887189,0.001632417,0.003754462,0.00009096715,0.00005380494,0.00004644588,0.001338547,0.00001374025,0.004350736],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00172402,"threshold_uncertainty_score":0.005767465,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01867305978265335,"score_gpt":0.2512727232847591,"score_spread":0.2325996635021058,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}