{"id":"W4313147584","doi":"10.1136/ijgc-2022-esgo.488","title":"2022-RA-249-ESGO Overall survival results from ariel3: a phase 3 randomised, double-blind study of rucaparib vs placebo following response to platinum-based chemotherapy for recurrent ovarian carcinoma","year":2022,"lang":"en","type":"article","venue":"International Journal of Gynecological Cancer","topic":"PARP inhibition in cancer therapy","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; Ottawa Hospital; University Health Network","funders":"","keywords":"Medicine; Internal medicine; Clinical endpoint; Placebo; Oncology; Regimen; Population; Chemotherapy regimen; Chemotherapy; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001980482,0.00161169,0.003766918,0.0005838024,0.0004473822,0.001207715,0.001152309,0.002221334,0.008676441],"category_scores_gemma":[0.001231107,0.0007141239,0.002488828,0.0004657058,0.001374107,0.0009935526,0.0003622109,0.004553059,0.00175598],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006247042,"about_ca_system_score_gemma":0.001104512,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001028385,"about_ca_topic_score_gemma":0.002565348,"domain_scores_codex":[0.9993844,0.0003170311,0.00003277178,0.00008870703,0.00004696159,0.0001301272],"domain_scores_gemma":[0.9992158,0.0002150868,0.000129529,0.00007908955,0.00004596205,0.0003144755],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9646153,0.007842266,0.0002825857,0.0004756381,0.0008685387,0.0000382638,0.00003940962,0.0003588128,0.00657324,0.00009361129,0.0009847226,0.01782764],"study_design_scores_gemma":[0.8977115,0.09831437,0.001786243,0.00001978705,0.000376007,0.00002949339,0.00001820815,0.0002984408,0.0007388113,0.00008025251,0.0006067341,0.00002009896],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9861742,0.004754449,0.0006805178,0.0008155279,0.0006415012,0.001984291,0.001740937,0.0003411467,0.002867484],"genre_scores_gemma":[0.9841724,0.002305892,0.001067931,0.001438755,0.0006234805,0.002004237,0.002051295,0.00009220259,0.006243805],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008676441,"threshold_uncertainty_score":0.02902555,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07666200252183013,"score_gpt":0.3994733332075067,"score_spread":0.3228113306856766,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}