{"id":"W4313178328","doi":"10.1007/978-3-031-11363-5_9","title":"Interleukin-1 Targeted Agents","year":2022,"lang":"en","type":"book-chapter","venue":"","topic":"Autoimmune and Inflammatory Disorders Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Medicine; Canakinumab; Anakinra; Discontinuation; Intensive care medicine; Randomized controlled trial; Pneumonia; Respiratory tract infections; Disease; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001111416,0.0005306466,0.0002276184,0.0004580901,0.0001607546,0.0007639039,0.0003439906,0.0005084271,0.0340814],"category_scores_gemma":[0.0001486588,0.0001380661,0.0001730816,0.0002733368,0.0001585363,0.0005830362,0.0004322475,0.001269194,0.02080679],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003039814,"about_ca_system_score_gemma":0.0002182937,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002654883,"about_ca_topic_score_gemma":0.001131085,"domain_scores_codex":[0.9999352,0.000008063162,0.000001858325,0.000009042067,0.00003630924,0.000009430137],"domain_scores_gemma":[0.9999707,0.00001179602,0.000003841293,0.000002685737,0.000005474682,0.000005577499],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008211334,0.0001061609,0.00005024871,0.0004723395,0.00001145565,0.0002082008,0.00005627219,0.000351376,0.0140318,0.02410829,0.3572022,0.6033195],"study_design_scores_gemma":[0.000008748269,0.00003167454,0.00006718609,0.0001097374,0.000004505731,0.0003398157,0.000008135935,0.00007045388,0.001629197,0.002518881,0.9952082,0.00000348673],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.002760862,0.273594,0.01199939,0.003786612,0.006051402,0.0001056622,0.0004889751,0.0006231392,0.70059],"genre_scores_gemma":[0.007957457,0.1040353,0.003777114,0.003654595,0.0009990586,0.00009978845,0.0003417971,0.0001014304,0.8790334],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.0340814,"threshold_uncertainty_score":0.1140136,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03765424852415371,"score_gpt":0.2980267073157237,"score_spread":0.2603724587915699,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}