{"id":"W4313222782","doi":"10.1111/mmi.15021","title":"Lack of evidence that <i>Pseudomonas aeruginosa</i><scp>AmpDh3‐PA0808</scp> constitute a type <scp>VI</scp> secretion system effector–immunity pair","year":2022,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Canada Foundation for Innovation","keywords":"Biology; Peptidoglycan; Periplasmic space; Type VI secretion system; Effector; Secretion; Cell biology; Cell envelope; Pseudomonas aeruginosa; Microbiology; Cytosol; Bacteria; Biochemistry; Cell wall; Enzyme; Escherichia coli; Virulence; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005183406,0.000216744,0.000254584,0.0003176256,0.0002360012,0.0006006148,0.0006547521,0.000629906,0.004087132],"category_scores_gemma":[0.001021639,0.0001205873,0.0004744,0.0002898904,0.0004116577,0.0004974424,0.0003804581,0.0006332247,0.001638616],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003229367,"about_ca_system_score_gemma":0.0003146545,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008469853,"about_ca_topic_score_gemma":0.0007990973,"domain_scores_codex":[0.9993764,0.00007668052,0.00005978097,0.0001247624,0.0002891504,0.00007331135],"domain_scores_gemma":[0.9985785,0.0004326402,0.0002695406,0.000219188,0.0003341654,0.00016593],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003544655,0.0001764603,0.02452609,0.0004389436,0.000114251,0.0006651456,0.0001115254,0.0000744764,0.9601654,0.0005203743,0.0006551564,0.0121977],"study_design_scores_gemma":[0.00003354706,0.001309008,0.1534047,0.0001217738,0.0003435733,0.01293823,0.0005755834,0.001900514,0.7720091,0.00133801,0.05599003,0.00003579918],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9791608,0.001612148,0.005612809,0.0008664965,0.0001113369,0.00003290266,0.001284022,0.0001950416,0.01112435],"genre_scores_gemma":[0.9913918,0.0005989009,0.002915043,0.0003966243,0.00003715082,0.00001917333,0.002180501,0.00003568761,0.002425114],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004087132,"threshold_uncertainty_score":0.01367277,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04890554495230404,"score_gpt":0.2906871991745743,"score_spread":0.2417816542222703,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}