{"id":"W4313311892","doi":"10.1155/2022/7067623","title":"Metabolism‐Related Gene TXNRD1 Regulates Inflammation and Oxidative Stress Induced by Cigarette Smoke through the Nrf2/HO‐1 Pathway in the Small Airway Epithelium","year":2022,"lang":"en","type":"article","venue":"Oxidative Medicine and Cellular Longevity","topic":"Chronic Obstructive Pulmonary Disease (COPD) Research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"National Natural Science Foundation of China","keywords":"COPD; Oxidative stress; Inflammation; Downregulation and upregulation; Biology; Cancer research; Immunology; Chemistry; Gene; Medicine; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001326181,0.0002545476,0.0004332572,0.0004606715,0.0003206756,0.0003430623,0.000114144,0.0001809592,0.001690127],"category_scores_gemma":[0.0001356305,0.0001369803,0.0005615197,0.0007349864,0.0001291808,0.0001984258,0.0002863221,0.0003066261,0.0002706001],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002886163,"about_ca_system_score_gemma":0.0002990807,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001476351,"about_ca_topic_score_gemma":0.00159511,"domain_scores_codex":[0.9998621,0.00001295038,0.00001094609,0.00004844067,0.00003790122,0.00002767391],"domain_scores_gemma":[0.9999329,0.000007228003,0.00002251968,0.00000479256,0.00001989729,0.00001264117],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001464542,0.0001129544,0.0499828,0.001080682,0.0001992396,0.0004745867,0.0002347974,0.0006729412,0.9219818,0.0004322696,0.001717323,0.02164605],"study_design_scores_gemma":[0.0000879525,0.0005019784,0.6900826,0.0000997746,0.0005508219,0.001494686,0.0004651653,0.006075947,0.2832416,0.000524612,0.01682911,0.00004571496],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.978413,0.008091344,0.002151334,0.0002226979,0.00005323476,0.0000374677,0.008967032,0.0001452097,0.001918774],"genre_scores_gemma":[0.9790461,0.004108915,0.002642164,0.0001624078,0.00001630077,0.00008669499,0.01013785,0.00002888418,0.003770568],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001690127,"threshold_uncertainty_score":0.005654037,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02690637312878387,"score_gpt":0.2646005095510141,"score_spread":0.2376941364222302,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}