{"id":"W4313315913","doi":"10.1371/journal.pone.0279912","title":"StarD7 deficiency hinders cell motility through p-ERK1/2/Cx43 reduction","year":2022,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Fondo para la Investigación Científica y Tecnológica; Universitat Autònoma de Barcelona; Gillings School of Public Health; Fundació Institut de Recerca Hospital Universitari Vall d’Hebron; Queen's University; Consejo Nacional de Investigaciones Científicas y Técnicas","keywords":"Cell biology; Gene knockdown; Gene silencing; Biology; Motility; Cell migration; Mitochondrion; Ectopic expression; Golgi apparatus; Cytosol; Gene isoform; Cell; Downregulation and upregulation; Signal transduction; Cell culture; Biochemistry; Genetics; Endoplasmic reticulum","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009891333,0.0003146359,0.0003399314,0.0002778285,0.0001814152,0.0002386391,0.0001969573,0.0003032624,0.0016561],"category_scores_gemma":[0.00005965173,0.0001562247,0.0003147703,0.0001404324,0.0002591496,0.0001906693,0.0001828929,0.0005974321,0.0003760553],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002631537,"about_ca_system_score_gemma":0.0002629491,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006883134,"about_ca_topic_score_gemma":0.00118424,"domain_scores_codex":[0.9998589,0.00001584677,0.00002020366,0.00002945076,0.00004015044,0.00003537274],"domain_scores_gemma":[0.9999024,0.00001110093,0.0000193119,0.000008686691,0.00001239214,0.00004608012],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001013915,0.00002829491,0.00009239437,0.00003830716,0.000004403414,0.00005526578,0.0000120049,0.00002784551,0.9989987,0.00009654291,0.00004195491,0.0005029272],"study_design_scores_gemma":[0.00001404887,0.0002205142,0.002925572,0.000005127045,0.00001454896,0.0001401933,0.00003727659,0.001008962,0.9935338,0.00004301416,0.002053145,0.000003647921],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943318,0.001254341,0.001737187,0.00015425,0.00005703881,0.00002572643,0.0005526377,0.0001226562,0.001764403],"genre_scores_gemma":[0.9901737,0.001214537,0.001708073,0.00006561576,0.000008790351,0.00005984289,0.0008484694,0.00004030798,0.005880703],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0016561,"threshold_uncertainty_score":0.005540133,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03519910274455108,"score_gpt":0.2198087939855318,"score_spread":0.1846096912409807,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}