{"id":"W4313339685","doi":"10.1016/j.lfs.2022.121330","title":"MOTS-c and aerobic exercise induce cardiac physiological adaptation via NRG1/ErbB4/CEBPβ modification in rats","year":2022,"lang":"en","type":"article","venue":"Life Sciences","topic":"GDF15 and Related Biomarkers","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"National Natural Science Foundation of China","keywords":"Cardiac function curve; Aerobic exercise; Internal medicine; H&E stain; Medicine; Heart rate; Endocrinology; Cardiology; Chemistry; Blood pressure; Heart failure; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005601308,0.00007979579,0.0001645309,0.0001355244,0.0002624361,0.00001393152,0.00009412543,0.00005673555,0.00003975908],"category_scores_gemma":[0.00005305702,0.00005864461,0.00003524755,0.0006701715,0.0002346212,0.000102377,0.00005934033,0.000172276,0.000007331675],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003546033,"about_ca_system_score_gemma":0.00009854984,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001087197,"about_ca_topic_score_gemma":0.000001862103,"domain_scores_codex":[0.9989337,0.00009933163,0.0001659447,0.0003077243,0.0003184613,0.000174792],"domain_scores_gemma":[0.9996971,0.0000351385,0.00006010713,0.00009924055,0.00001810617,0.00009030333],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0006636897,0.0007970775,0.06890324,0.0001229372,0.00007454389,0.00004934723,0.008749573,0.008988922,0.82918,0.0007312912,0.01009203,0.07164735],"study_design_scores_gemma":[0.001657003,0.001275735,0.9071916,0.0001134791,0.0001074107,0.00003474353,0.01368329,0.06682578,0.005421553,0.001155618,0.002063644,0.0004701239],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959485,0.001262929,0.00001824048,0.001520008,0.0002626259,0.0002906701,0.000001884226,0.00002822927,0.0006669098],"genre_scores_gemma":[0.9989321,0.0002546178,0.0003270101,0.0002534766,0.00004389265,0.00004533807,0.00001371446,0.000003459911,0.0001263747],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8382884,"threshold_uncertainty_score":0.2391458,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05435383229672514,"score_gpt":0.2898189393950135,"score_spread":0.2354651070982883,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}