{"id":"W4313355963","doi":"10.4049/jimmunol.198.supp.82.35","title":"A Minimum Conditioning Protocol towards Transplantation Tolerance in NOD Mice by Mixed Hematopoietic Chimerism","year":2017,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Busulfan; Immunology; Transplantation Chimera; Nod; Bone marrow; Haematopoiesis; CD8; Transplantation; Biology; Chimera (genetics); Clonal deletion; Hematopoietic stem cell transplantation; Antigen; Stem cell; Immune system; T cell; Medicine; Internal medicine; Hematopoietic cell; Diabetes mellitus; Endocrinology; Genetics; T-cell receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000537418,0.0004213818,0.0003472745,0.0003651379,0.000255237,0.0003112173,0.0004022094,0.0003588517,0.001953283],"category_scores_gemma":[0.0002285768,0.0002101618,0.000304787,0.0001589071,0.0002217971,0.0001886952,0.0003054762,0.00103281,0.0004259719],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002447666,"about_ca_system_score_gemma":0.0002692644,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001680033,"about_ca_topic_score_gemma":0.000251223,"domain_scores_codex":[0.9996176,0.00008198933,0.00005314495,0.00007152021,0.0001153324,0.00006035203],"domain_scores_gemma":[0.9997519,0.00003436109,0.00007692678,0.00004723267,0.00002829994,0.00006147542],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002144477,0.0001316324,0.0001258269,0.00003802681,0.000004131794,0.00001808974,0.00001119625,0.00011761,0.9975495,0.0002553702,0.00005996651,0.001474217],"study_design_scores_gemma":[0.00005903552,0.001412356,0.001367152,0.00002083757,0.00002300831,0.0002131771,0.000007843212,0.0009063502,0.9932548,0.00009165172,0.002638135,0.00000569619],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9552245,0.0009674216,0.03825603,0.000175556,0.00008353414,0.001039781,0.0006974705,0.0004839879,0.003071608],"genre_scores_gemma":[0.9592879,0.0005829947,0.03513664,0.0002036817,0.00003007803,0.001151118,0.0009754845,0.00009321635,0.002538928],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001953283,"threshold_uncertainty_score":0.006534338,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0161783796651726,"score_gpt":0.2989480607679226,"score_spread":0.28276968110275,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}