{"id":"W4313356410","doi":"10.4049/jimmunol.196.supp.216.21","title":"Functional differences exist in contribution of VH and VL from polyspecific IgM and monospecific IgG antibodies in antigen recognition and virus neutralization functions.","year":2016,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"Neutralization; Antigen; Antibody; Epitope; Biology; Virology; Virus; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001333362,0.0001299204,0.00006472045,0.00013615,0.00006062064,0.0001588501,0.0001432019,0.0001438741,0.001096105],"category_scores_gemma":[0.0001185622,0.00004878804,0.0001740058,0.00007779741,0.00007094589,0.0001027663,0.0001018444,0.0001422692,0.0001607857],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001808961,"about_ca_system_score_gemma":0.00009194627,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006428408,"about_ca_topic_score_gemma":0.000628171,"domain_scores_codex":[0.999916,0.0000130881,0.000005832877,0.00001408274,0.00002471168,0.00002636625],"domain_scores_gemma":[0.9999577,0.00001008296,0.000009823401,0.000004038365,0.000008353534,0.00001010351],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006026873,0.000009081507,0.00144103,0.00002534242,0.000007218958,0.00004431943,0.00001303723,0.00004980939,0.9961352,0.00007718963,0.00002093506,0.002116557],"study_design_scores_gemma":[0.00001364229,0.0003742829,0.05869289,0.00001087754,0.00006012904,0.0007804044,0.00005616693,0.001480672,0.9341061,0.0001310103,0.004288421,0.000005413302],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997636,0.0005997217,0.001007931,0.00001845363,0.000006190537,0.000004422975,0.00009612541,0.00001102455,0.0006201619],"genre_scores_gemma":[0.9977107,0.0001823466,0.000711568,0.00002268733,0.000002919742,0.000004190015,0.000485543,0.00000332295,0.0008767314],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001096105,"threshold_uncertainty_score":0.003666818,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04891760155497556,"score_gpt":0.2722927514179117,"score_spread":0.2233751498629362,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}