{"id":"W4313361247","doi":"10.3390/ijms24010598","title":"Regulation of K+-Dependent Na+/Ca2+-Exchangers (NCKX)","year":2022,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Libin Cardiovascular Institute of Alberta; University of Calgary","funders":"Canadian Institutes of Health Research; University of Calgary","keywords":"Allosteric regulation; Transporter; Cell biology; Homeostasis; Regulation of gene expression; Biochemistry; Biology; Gene expression; Calcium signaling; Chemistry; Signal transduction; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002718906,0.0007003326,0.0008290171,0.001239805,0.0002160699,0.0006480437,0.0006321564,0.0007563637,0.002408326],"category_scores_gemma":[0.0003344236,0.0001872126,0.0003118886,0.001232556,0.0003048614,0.0009985922,0.0004604036,0.001086584,0.002269701],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004790823,"about_ca_system_score_gemma":0.0007679065,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006868005,"about_ca_topic_score_gemma":0.001179187,"domain_scores_codex":[0.999912,0.00001098768,0.00001241683,0.0000201876,0.00003278386,0.00001163691],"domain_scores_gemma":[0.9998939,0.00003578195,0.00001713016,0.000003747447,0.00003616774,0.00001322926],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009508952,0.00005372384,0.0001844012,0.01732681,0.0000721004,0.0002931081,0.00006196888,0.0005308209,0.008131088,0.007044626,0.02607979,0.9401264],"study_design_scores_gemma":[0.00001445108,0.00009726717,0.0009466712,0.001448111,0.00007288004,0.001296755,0.00004732157,0.0001188088,0.001372589,0.002169439,0.9923993,0.00001656006],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000243058,0.9975094,0.0001990764,0.000212453,0.0002527406,0.00000484575,0.00002173003,0.00001013028,0.001546567],"genre_scores_gemma":[0.000844437,0.9978384,0.0002040291,0.0001194834,0.0001122355,0.00000614413,0.00003114328,0.000001343646,0.0008427615],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002408326,"threshold_uncertainty_score":0.008056641,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09471086573392826,"score_gpt":0.3670059186499431,"score_spread":0.2722950529160149,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}