{"id":"W4313369073","doi":"10.4049/jimmunol.204.supp.160.10","title":"Treatment with Multiple-linked Myelin Peptides Encapsulated within Nanoparticles Induces Antigen-specific Tolerance in SJL/J Relapsing-remitting Experimental Autoimmune Encephalomyelitis","year":2020,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Experimental autoimmune encephalomyelitis; Myelin; Multiple sclerosis; Myelin basic protein; Proteolipid protein 1; Immunology; Peptide; Epitope; Antigen; Myelin proteolipid protein; Biology; Encephalomyelitis; Central nervous system; Molecular biology; Biochemistry; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003391989,0.0007178892,0.0006828308,0.0004020331,0.0002155847,0.0003138829,0.0002697452,0.0007128212,0.0008821494],"category_scores_gemma":[0.0001681284,0.0002458964,0.0004747142,0.0001596045,0.0003179507,0.0003107153,0.000151508,0.001307953,0.000322737],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002025259,"about_ca_system_score_gemma":0.0002222936,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003927169,"about_ca_topic_score_gemma":0.0005887906,"domain_scores_codex":[0.9996639,0.00004515344,0.00004438207,0.00006436426,0.00007693475,0.0001052357],"domain_scores_gemma":[0.9997677,0.00003679181,0.00006601962,0.00002163436,0.00002954932,0.00007826824],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004814278,0.000458559,0.000048046,0.00004106701,0.000005737177,0.00003250711,0.00001257876,0.00003889908,0.9982793,0.00001811038,0.00003055504,0.0005533401],"study_design_scores_gemma":[0.0002061772,0.009783204,0.001766638,0.00001145213,0.00003425897,0.0001449939,0.0000251482,0.0006861701,0.9867277,0.00002805185,0.0005795941,0.000006685939],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972434,0.0005696659,0.001108452,0.00007747112,0.0001004707,0.00007187423,0.0001361968,0.00008973721,0.0006027824],"genre_scores_gemma":[0.9952841,0.0005905752,0.001390823,0.0001111511,0.00005157235,0.00009514989,0.0002745254,0.00002968139,0.002172304],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008821494,"threshold_uncertainty_score":0.002951086,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02265232134674543,"score_gpt":0.2423709152776371,"score_spread":0.2197185939308917,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}